New PET scan could spot liver cancer spread more clearly

NCT ID NCT05176223

First seen Feb 05, 2026 · Last updated Jun 23, 2026 · Updated 15 times

Summary

This phase II trial at Mayo Clinic tested whether a special PET scan using 68Ga-PSMA can better detect and track advanced liver cancer that has spread. The radioactive tracer attaches to a protein found on liver cancer cells, making them visible on the scan. The study enrolled 29 adults with advanced liver cancer not treatable by surgery, aiming to see if this imaging improves diagnosis and management compared to standard methods.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ADVANCED HEPATOCELLULAR CARCINOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Gallium Ga 68 Gozetotide (68Ga-PSMA)

What this could lead to

If successful, this imaging method could help doctors better detect and monitor advanced liver cancer, potentially leading to more personalized treatment decisions.

What could go wrong

This is a small, early-phase study with only 29 participants, so results may not apply to all patients. The imaging technique is still experimental and not yet standard practice.

Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.