Preterm Drug's hidden impact? 6-Year study on Kids' brains begins

NCT ID NCT07146451

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 480 children born to mothers who received either nifedipine or a placebo after early rupture of membranes (22-33 weeks). Researchers will assess the children at age 6 for cerebral palsy, coordination, language, behavior, and thinking skills using parent questionnaires and online tests. The goal is to see if nifedipine exposure before birth has any long-term effects on neurodevelopment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

nifedipine

What this could lead to

If successful, this could show whether nifedipine is safe for children's long-term brain development after preterm birth.

What could go wrong

This is an observational follow-up, not a new treatment test. Results depend on parent reports and may not prove cause and effect.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Premature Birth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Trousseau University Hospital

    RECRUITING

    Paris, France, 75012, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••