Cure My Disease

Don't miss your cure!

 Log in / Sign up

Could a ceramic barrier rebuild jawbone better than metal mesh?

NCT ID NCT07700095

Disease control Sponsor: Hams Hamed Abdelrahman Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This trial tests whether custom-made 3D zirconia barriers can rebuild severely thinned jawbone better than the standard pre-bent titanium mesh. Sixteen people with significant bone loss in the lower jaw will receive one of the two materials during a first surgery, followed by dental implant placement later. The study measures changes in bone height, width, and volume, as well as infection and wound healing. Zirconia may offer better biocompatibility and easier removal than titanium.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
customized zirconia barrier
What this could lead to
If successful, this could offer a more biocompatible and easier-to-use alternative to titanium mesh for rebuilding jawbone, potentially improving dental implant success.
What could go wrong
This is a small early-stage trial with only 16 participants, so results may not apply broadly. Zirconia barriers could still cause infection or wound healing problems.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 16 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2024

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients are systemically medically free according to the American Society of Anesthesiologists (ASA) considered as ASA I. * Ability to maintain good oral hygiene as evidenced in recall visits. * patients who had a partial or completely edentulous alveolar ridge with apparent 3D defect following teeth loss. * All patients were free from any local or general disease that may interfere with bone healing and had no history of previous grafting procedure at the designated edentulous ridge. * The ridge had to exhibit severe vertical and horizontal (3D) alveolar ridge deficiency with alveolar ridge height less than 7 mm from the alveolar crest to the inferior alveolar canal and width less than 5 mm which was firstly measured by CBCT, or a clinically apparent increase in inter-arch space relative to the adjacent natural teeth. * Pre-operative clinical assessment of soft tissue coverage was done to cover the graft and its membrane, in addition to assessment of occlusion and inter-arch distance should allow for the graft, membrane, implan and the future prosthesis. Exclusion Criteria: * Smoker (\> 25 cigarettes/ day). * Patients undergoing radiotherapy or chemotherapy * Patients having infection or local lesions in the area of surgery. * Patients with diabetes mellitus or bone diseases which may compromise the results. * Patient with poor oral hygiene or active periodontal disease. * Patient with limited mouth opening. * Participation in other clinical trials

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Mandibular atrophy are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Mandibular atrophy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Kafr El-sheikh University

    RECRUITING

    Kafr Elsheikh, Egypt