Can 3D-Printed crowns match milled ones for tough molar repairs?

NCT ID NCT06850649

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time

Summary

This trial tests whether 3D-printed endocrowns—a type of dental crown that replaces the top of a tooth—are as durable and good-looking as milled ones for molars with severe tooth loss. About 33 adults with healthy gums and at least two remaining tooth walls will receive either a 3D-printed or milled crown. Over two years, dentists will check for color changes, fit, wear, sensitivity, and decay to see which method holds up better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Endocrowns made from different materials (IPS Empress CAD, Vita Enamic, VarseoSmile Crown Plus) using 3D-printing or milling
What this could lead to
If successful, this could point toward more durable and cost-effective dental restorations for severely damaged molars.
What could go wrong
This is a small, early-stage trial, and results may not apply to all patients. Endocrowns may fail over time, leading to fractures or the need for replacement.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

33 people

The number who actually took part.

Started

May 2023

Finished

May 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 90 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Must be a lower or upper molar tooth * Must be periodontal healthy * There must be at least two axial walls in the relevant tooth * Gingival steps should be at gum level * There must be neighboring teeth mesial and distal to the relevant tooth. * The place where it occludes must be the opposing tooth and the tooth must be a natural or filled tooth without a prosthesis. * No systemic acut or chronic conditions (Thyroid disease, Alzheimer's Disease, Insulin dependent diabetes, etc.) Exclusion Criteria: * Inadequate oral hygiene, bleeding on probing, pocket deeper than 3 mm mobility presence * Sensitivity to percussion after root canal treatment * Insufficient enamel tissue remaining in the relevant tooth * Presence of radiographically abnormal periodontal space * Teeth with inadequate bone support * Teeth with root resorption and fracture

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ege University

    Izmir, 35100, Turkey (Türkiye)