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A pill that fights warts from the inside: trial puts immune-regulating capsule to the test

NCT ID NCT03977753

Disease control Sponsor: Labo'Life Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 31, 2026 · Last updated Sep 01, 2026 · Updated 1 time

Summary

This trial tests whether a daily oral capsule called 2LVERU can clear common, flat, or plantar warts caused by HPV. Researchers compare the capsule against a placebo in 162 people aged 3 and older over 6 months. The main question is whether warts disappear completely by the end of treatment, with follow-up checks at 4 and 9 months to see how well it works and whether warts return.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
2LVERU or 2LVERU JUNIOR, an oral immune-regulating capsule taken daily for 6 months
What this could lead to
If it works, this could offer a non-invasive, at-home treatment that clears warts without burning, freezing, or surgery.
What could go wrong
This is a phase 4 trial with 162 participants, and warts often clear on their own, so the placebo response may be high. The treatment may not work for everyone, and recurrence is possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 162 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2020

Expected to finish

Feb 2029

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

3 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients, male or female, aged 3 years and older, * Patients with common warts (Verruca vulgaris), and/or plantar warts (Verruca plantaris), and/or flat warts (Verruca plana), * Patients (and/or parents if necessary) having the faculties to understand and respect the constraints of the study, * Signature of the Informed Consent Form by the patient (and/or parents if necessary). Exclusion Criteria: * Patients who have received any curative warts treatment in the previous 2 months prior to the study, * Patients who have received any homeopathic treatment in the previous 2 months prior to the study, * Patients under immunosuppressive treatment, * Patients having received immunotherapy or micro-immunotherapy during the last 6 months, * Patients with known lactose intolerance, * Pregnant or breastfeeding women, * Patients who participated in a clinical study in the previous 2-months period, * Patients (and/or parents of patients if necessary) who are not sufficiently motivated to engage on the total study follow-up period, or likely to travel or to move before the end of the study, * Patients with severe immunodeficiency disease requiring long term treatment (\*) or patients under chemotherapy or radiotherapy, * Patients under listed homeopathic or phytotherapy treatment (see protocol), * Patients addicted to or using recreational drugs, * Patient under guardianship and/or curators, (\*) important renal or respiratory insufficiency, transplanted or grafted patients, HIV/AIDS, terminal cancer.

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Conditions

The condition(s) this trial relates to.

common wart plantar wart

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Common wart Flat wart Plantar wart

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    5 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Clinique Saint-Luc (Bouge)

    RECRUITING

    Bouge, 5004, Belgium

  • Private Practice

    RECRUITING

    Ghent, 9942, Belgium

  • Private Practice

    TERMINATED

    Oisquercq, 1480, Belgium

  • Private Practice

    RECRUITING

    Saint-Symphorien, 7030, Belgium

  • Private Practice

    RECRUITING

    Seneffe, 7180, Belgium

  • Private Practice

    RECRUITING

    Wavre, 1300, Belgium

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