Promising radioactive treatment shows up to 75% response in tough childhood cancer

NCT ID NCT01163383

First seen Apr 19, 2026 · Last updated May 01, 2026 · Updated 3 times

Summary

This expanded access program provides a radioactive drug called 131 I-MIBG to children (age 1 and older) with neuroblastoma that has not responded to standard treatments or has come back. The drug targets and kills cancer cells with radiation. Early results from a related study showed that adding another drug (vorinostat) led to a 75% response rate after two cycles, though this combination is not yet FDA-approved for neuroblastoma. The goal is to offer treatment while collecting more data on safety and effectiveness.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • The Children's Hospital of Philadelphia

    AVAILABLE

    Philadelphia, Pennsylvania, 19104, United States

Conditions

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