Radioactive therapy shows promise for tough childhood cancer

NCT ID NCT01163383

First seen Apr 19, 2026 · Last updated Jun 10, 2026 · Updated 12 times

Summary

This expanded access program provides a radioactive drug called 131 I-MIBG to children aged 1 year and older with neuroblastoma that has not responded to standard treatments or has returned. The drug delivers radiation directly to cancer cells to kill them. The program also collects information on how well the treatment works and its side effects. Early results from a related study showed that combining MIBG with another drug called vorinostat led to a 75% response rate after two cycles.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • The Children's Hospital of Philadelphia

    AVAILABLE

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.