New Gas-Based MRI could replace X-Rays for baby lungs

NCT ID NCT04995562

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new way to take pictures of babies' lungs using MRI with a special inhaled gas (129Xe) instead of X-rays or CT scans, which use radiation. The goal is to safely see how well the lungs are working in infants with breathing problems. About 12 infants in the NICU will be enrolled to measure lung ventilation and structure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
inhaled hyperpolarized 129Xe gas
What this could lead to
If successful, this could provide a safer, radiation-free way to diagnose and monitor lung problems in newborns.
What could go wrong
This is a very small early-phase study (12 infants) focused on imaging feasibility, not treatment. The gas is inhaled and may not work well in all infants.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Megan Schmitt

    RECRUITING

    Cincinnati, Ohio, 45229, United States