New drug candidate aims to calm restless legs when current meds backfire
Symptom relief
Completed
This small study tested whether ecopipam, a drug that blocks a specific brain receptor, can help people with restless leg syndrome whose symptoms have gotten worse from their usual dopamine-based medication. Ten adults took either ecopipam or a placebo for six weeks, then switche…
Phase: PHASE1, PHASE2 • Sponsor: William Ondo, MD • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC