Magic mushroom compound may quiet the depressed Brain's endless Self-Criticism
Symptom relief
Recruiting now
This study investigates whether a single dose of psilocybin, the active compound in magic mushrooms, can reduce rumination—repetitive negative self-focused thinking—in people with major depressive disorder. Researchers will use brain scans to see how psilocybin changes activity i…
Phase: PHASE3 • Sponsor: Sharmin Ghaznavi • Aim: Symptom relief
Last updated Jul 19, 2026 00:00 UTC