Hôpital Le Vinatier

This study tests whether training mental health professionals to deliver a short psychoeducational program (BREF) can reduce the burden on caregivers of people with schizophrenia or first psychotic episode. The trial will include 206 caregivers, comparing those who receive the pr…

This study tests whether bright light therapy can help people going through cocaine withdrawal in a hospital. Cocaine withdrawal often disrupts sleep, mood, and daily rhythms, making it hard to stay drug-free. The therapy uses a special lamp to mimic daylight, which may improve s…

This study tests whether a non-invasive brain stimulation technique called tDCS can help adults with Down syndrome who have depression with catatonia (a state of being unresponsive or stuck). 62 participants will receive either real or fake (sham) tDCS for 15 sessions over 5 days…

This study tests a new psychoeducation program led by an advanced practice nurse to reduce the burden on family caregivers of young adults (ages 18-35) who have had a first psychotic episode. The program includes individual and group sessions to support caregivers. Researchers wi…

This study aims to create a French-language memory task that can be used during brain scans to measure source-monitoring—the ability to remember where information came from. Researchers will test the task on 120 people, including those with schizophrenia and healthy volunteers. T…

This study follows 32 people with cocaine use disorder as they go through detox. Researchers use wearable sleep monitors, questionnaires, and urine tests to track sleep quality and body rhythms during active use, early withdrawal, and late withdrawal. The goal is to understand ho…

This study looks at how early-life trauma changes the way the brain releases dopamine when smelling pleasant odors. Researchers will use brain scans to compare 15 adults with a history of trauma and 15 without. The goal is to understand the link between trauma, smell perception, …

This study looks at how the brain processes time and attention after losing a loved one to suicide, homicide, or accident. Researchers will measure brain waves in 61 adults who experienced such a loss recently. The goal is to find early signs that may lead to PTSD or depression, …

This study looks at how dopamine, a brain chemical, influences our ability to remember whether something really happened or was just imagined. Researchers will give healthy volunteers either a dopamine-boosting drug, a dopamine-blocking drug, or a placebo, then test their memory.…

This pilot study will screen 150 homeless adults in French shelters for autism, ADHD, and intellectual disability using interviews and questionnaires. The goal is to find out how many have these conditions, which may have contributed to their homelessness. Results could help tail…

This study tests whether a 3-day training program called REFOCUS helps mental health teams provide care that supports personal recovery. About 760 people with severe mental disorders (like schizophrenia or bipolar disorder) will take part across 18 centers. Researchers will measu…

This study tests whether a program combining peer support (someone with lived experience of mental health issues) and a 'Hope Box' (a box filled with personal items that bring comfort and hope) can help people hospitalized after a suicide attempt. About 40 patients will receive t…

This study looks at how adults with intellectual developmental disorder (IDD) understand emotions, compared to people without IDD. Researchers will test 60 adults using tasks that involve recognizing facial expressions, emotions in context, and vocal tones. The goal is to find sp…