Denovo Biopharma Llc
Clinical trials sponsored by Denovo Biopharma Llc, explained in plain language.
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New schizophrenia drug targets brain glutamate, not dopamine
Symptom relief CompletedResearchers are testing whether the experimental drug LY2140023 (pomaglumetad methionil) reduces schizophrenia symptoms better than a placebo. The trial enrolls adults diagnosed with schizophrenia who stay in a hospital or clinic during the four-week study. Participants take the …
Phase 2 • Sponsor: Denovo Biopharma LLC • Aim: Symptom relief
Last updated Sep 16, 2026 00:00 UTC
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New drug candidate takes aim at schizophrenia symptoms
Symptom relief CompletedResearchers are testing whether an experimental drug, LY2140023, eases schizophrenia symptoms better than placebo in people who are acutely ill. The trial also compares it to risperidone, an approved antipsychotic. About 1,100 patients with schizophrenia join this phase 2 study. …
Phase 2 • Sponsor: Denovo Biopharma LLC • Aim: Symptom relief
Last updated Sep 16, 2026 00:00 UTC
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Urine chemistry may hold key to safer dosing for brain drug
Knowledge-focused CompletedResearchers are testing whether making urine more acidic or more alkaline changes how the body processes an experimental drug called pomaglumetad methionil. In this Phase 1 study, 29 healthy volunteers receive the drug alone, with ammonium chloride to lower urine pH, or with sodi…
Phase 1 • Sponsor: Denovo Biopharma LLC • Aim: Knowledge-focused
Last updated Sep 17, 2026 00:00 UTC