Children's Cancer Group, China

This study is testing whether adding the drug rituximab early and intensively to a strong chemotherapy regimen can improve outcomes for children and teens with aggressive B-cell non-Hodgkin lymphoma. About 87 participants will receive the combination therapy. The goal is to see i…

This study compares two different ways of giving methotrexate (a chemotherapy drug) to children and teens newly diagnosed with T-cell lymphoblastic lymphoma, a rare cancer of the immune system. About 200 participants will be randomly assigned to one of two treatment plans to see …

This study is testing a drug called brentuximab vedotin, combined with chemotherapy, for children, adolescents, and young adults newly diagnosed with classical Hodgkin lymphoma. The goal is to see if this approach can achieve a faster and more complete response, allowing fewer pa…