VEXAS

Clinical trials for VEXAS explained in plain language.

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Trials to join now! 1 Not yet finished but already full! 1 Completed 1

Experimental drug pacritinib takes aim at rare inflammatory VEXAS syndrome

Disease control Recruiting now

This phase 1 trial tests the safety and tolerability of pacritinib, a pill that blocks JAK2 and IRAK1, in people with VEXAS syndrome—a rare, severe autoinflammatory disorder caused by a UBA1 gene mutation. Up to 15 participants will take pacritinib daily for up to 12 cycles, star…

Matched conditions: VEXAS

Phase 1 • Sponsor: Washington University School of Medicine • Aim: Disease control

Last updated Jul 17, 2026 00:00 UTC

VEXAS

Get alerted when new VEXAS trials appear

Experimental drug pacritinib takes aim at rare inflammatory VEXAS syndrome