VASODILATION

This study tests whether a drug called tadalafil (a vasodilator) and aerobic exercise can improve muscle function and blood flow in people with Duchenne muscular dystrophy (DMD). About 50 ambulatory children and adults with DMD will take part. The goal is to see if these approach…

This study looks at whether a lentil protein supplement is safe for healthy adults and if it can help control blood pressure, improve blood vessel function, and boost exercise performance. Researchers will give different doses to 48 healthy men and women aged 18 to 45 and monitor…

This study looks at how blood vessels in the arm widen when oxygen is low, and how this changes with menopause. Researchers will compare younger premenopausal women, perimenopausal women, and older postmenopausal women. No treatment is given; the goal is simply to understand the …

This study looks at how binge drinking in mid-life (ages 50-64) affects blood pressure, small blood vessels, and nerve activity. It compares binge drinkers to non-drinkers and moderate drinkers. In a second phase, binge drinkers will try 8 weeks of aerobic exercise to see if it i…

This study looks at how the nervous system and blood vessels work together to control blood pressure in healthy men and women. Researchers will measure nerve activity, blood flow, and responses to tiny doses of blood pressure medications. The goal is to understand if and why bloo…

This study tests whether a single 5-minute exposure to a special red light can increase blood flow in the calf muscles of people with peripheral artery disease (PAD). Forty adults with PAD will receive the light treatment, and researchers will measure blood flow changes using ult…