REGRESSION

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Hope for teens with down syndrome regression: three therapies put to the test

Disease control Ongoing

This study tests three medications—lorazepam, IVIG, and tofacitinib—in 66 people with Down syndrome (ages 8-30) who have developed a serious condition called Down Syndrome Regression Disorder (DSRD). DSRD causes sudden loss of skills, catatonia, and other severe symptoms. The goa…

Matched conditions: REGRESSION

Phase: PHASE2 • Sponsor: University of Colorado, Denver • Aim: Disease control

Last updated May 13, 2026 15:59 UTC

REGRESSION

Get alerted when new REGRESSION trials appear

Hope for teens with down syndrome regression: three therapies put to the test