CHRONIC GVHD
Clinical trials for CHRONIC GVHD explained in plain language.
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Extended drug trial aims to keep transplant Patients' blood counts stable
Disease control TerminatedThis was a follow-up study for people who had a stem cell transplant and then developed low blood cell counts (cytopenias). It aimed to see if taking the drug fostamatinib long-term (up to 21 more months) could safely help them maintain healthier levels of red blood cells or plat…
Matched conditions: CHRONIC GVHD
Phase: PHASE2 • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Experimental immune therapy offers hope for transplant patients with uncontrolled rejection
Disease control OngoingThis early-stage safety study is testing a new combination treatment for chronic graft-versus-host disease (cGVHD) that doesn't improve with standard steroid therapy. The treatment involves giving patients special anti-inflammatory immune cells (Tregs) collected from their origin…
Matched conditions: CHRONIC GVHD
Phase: PHASE1 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Remote care trial aims to ease suffering for transplant survivors
Symptom relief OngoingThis small study is testing whether monthly video calls with palliative care specialists are a practical and helpful way to support adults with moderate to severe chronic graft-versus-host disease (cGVHD). The goal is to help patients better manage their complex symptoms, reduce …
Matched conditions: CHRONIC GVHD
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Mar 27, 2026 12:38 UTC
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Scientists probe Skin's immune sentries in transplant complication
Knowledge-focused OngoingThis study aims to understand the role of specific immune cells, called dendritic cells, in the development of skin graft-versus-host disease (GVHD) after a bone marrow transplant. Researchers will collect and analyze small skin samples from 22 adult patients who have either acut…
Matched conditions: CHRONIC GVHD
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:41 UTC