Vernal keratoconjunctivitis
MONDO:0019085Vernal keratoconjunctivitis (VKC) is a chronic, severe allergy that affectsthe surfaces of the eyes. It most commonly occurs in boys living in warm, dry climates. Attacks associated with VKC are common in the spring (hence the name 'vernal') and summer but often reoccur in the winter. Signs and symptoms usually begin before 10 years of age and may include hard, cobblestone-like bumps (papillae) on the upper eyelid; sensitivity to light; redness; sticky mucus discharge; andinvoluntary blinking or spasms of the eyelid (blepharospasm).The condition usually subsides at the onset of puberty. It is caused by ahypersensitivity (allergic reaction)to airborne-allergens. Management focuses on preventing 'flare ups' and relieving the symptoms of the condition.
Also known as: Spring catarrh, Vernal Keratonconjunctivitis, VKC
2 clinical trials for this condition and its sub-types.
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New eye drop could ease severe allergy symptoms in kids and adults
Disease control Recruiting nowThis study tests whether adding diquafosol eye drops to standard treatment helps people with moderate-to-severe vernal keratoconjunctivitis (a serious eye allergy). About 94 participants aged 6 and older will receive either diquafosol plus cyclosporine or cyclosporine alone. Rese…
Phase 3 • Sponsor: The University of Hong Kong • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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New eye drop could ease severe allergy in kids
Disease control Recruiting nowThis study tests a new eye drop called T1695 against an existing treatment (ciclosporin) for children aged 4 to 17 with moderate to severe vernal keratoconjunctivitis, a serious allergic eye condition. About 120 participants will use the drops for 4 weeks to see which better redu…
Phase 2 • Sponsor: Laboratoires Thea • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC