Thymic neuroendocrine tumor
MONDO:0019964Thymic endocrine tumor is a rare, malignant, primary thymic neoplasm originating from neuroendocrine cells, presenting as a mass within the anterior mediastinum. Patients typically present with nonspecific symptoms, such as chest pain, cough, shortness of breath, or in some cases, superior vena cava syndrome, although patients could be asymptomatic during the early stages or present with multiple endocrine neoplasia type I. Ectopic production of ACTH and serotonin can lead to Cushing syndrome and carcinoid sydrome, respectively.
Also known as: neuroendocrine neoplasm of thymus, thymus NET, thymus neuroendocrine neoplasm, thymus neuroendocrine tumor, thymus neuroendocrine tumor, well differentiated, low or intermediate grade, thymus neuroendocrine tumour
1603 clinical trials for this condition and its sub-types, 3 tagged with Thymic neuroendocrine tumor itself.
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Browse by category →Sub-types of Thymic neuroendocrine tumor
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Thymic neuroendocrine carcinoma 3 trials
5 sub-types
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New drug shows promise in slowing advanced neuroendocrine tumors
Disease control OngoingThis study tests whether the drug cabozantinib can slow the growth of advanced neuroendocrine tumors (including carcinoid tumors) compared to a placebo. About 298 adults whose cancer worsened after prior treatment will receive either cabozantinib or a placebo pill. The main goal …
Phase 3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Aug 06, 2026 00:00 UTC
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New radioactive therapy targets hard-to-treat thyroid cancer
Disease control OngoingThis early-phase study tests a radioactive drug (177Lu-PP-F11N) that seeks out and attaches to cancer cells in people with advanced medullary thyroid cancer and certain other neuroendocrine tumors. The goal is to see if the drug can help image tumors and deliver targeted radiatio…
Phase 1 • Sponsor: University Hospital, Basel, Switzerland • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC