Sarcomatoid mesothelioma

MONDO:0006407

A diffuse malignant mesothelioma arising from the pleura and less often the peritoneum. It is characterized by the presence of spindle cells. Anaplastic morphologic features and multinucleated malignant cells may also be seen.

Also known as: malignant fibrous mesothelioma (morphologic abnormality), sarcomatoid mesothelioma, sarcomatoid mesothelioma (morphologic abnormality)

2741 clinical trials for this condition and its sub-types, 2 tagged with Sarcomatoid mesothelioma itself.

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Where it sits in the disease tree

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↑ Malignant mesothelioma (109)

Sub-types of Sarcomatoid mesothelioma

Pleural sarcomatoid mesothelioma 2 trials
Lymphohistiocytoid mesothelioma 0 trials

Including sub-types (2741) Tagged with Sarcomatoid mesothelioma (2)

Not yet finished but already full! 1 Completed 1

Immune booster shows promise against rare cancer

Disease control Completed

This study tested a drug called pembrolizumab in 65 people with malignant mesothelioma, a rare cancer of the lining around the lungs or abdomen. The drug works by helping the immune system attack cancer cells. The goal was to see if it could shrink tumors or slow the disease, but…

Phase 2 • Sponsor: University of Chicago • Aim: Disease control

Last updated Jun 27, 2026 12:30 UTC

Sarcomatoid mesothelioma

Where it sits in the disease tree

Immune booster shows promise against rare cancer