Rhabdomyosarcoma
MONDO:0005212A rare aggressive malignant mesenchymal neoplasm arising from skeletal muscle. It usually occurs in children and young adults. Only a small percentage of tumors arise in the skeletal muscle of the extremities. The majority arise in other anatomical sites.
Also known as: rhabdomyosarcoma, rhabdomyosarcoma (disease), rhabdomyosarcoma, malignant
2908 clinical trials for this condition and its sub-types, 99 tagged with Rhabdomyosarcoma itself.
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Sub-types of Rhabdomyosarcoma
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Alveolar rhabdomyosarcoma 9 trials
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Pleomorphic rhabdomyosarcoma 7 trials
2 sub-types
- Adult pleomorphic rhabdomyosarcoma 0 trials
- Childhood pleomorphic rhabdomyosarcoma 0 trials
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Embryonal rhabdomyosarcoma 4 trials
5 sub-types
- Botryoid rhabdomyosarcoma 2 trials Sub-types →
- Embryonal extrahepatic bile duct rhabdomyosarcoma 0 trials
- Orbit embryonal rhabdomyosarcoma 0 trials
- Parameningeal embryonal rhabdomyosarcoma 0 trials
- Prostate embryonal rhabdomyosarcoma 0 trials
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Spindle cell rhabdomyosarcoma 3 trials
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Testis rhabdomyosarcoma 1 trial
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Breast rhabdomyosarcoma 0 trials
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Gallbladder rhabdomyosarcoma 0 trials
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Liver rhabdomyosarcoma 0 trials
1 sub-type
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Mediastinum rhabdomyosarcoma 0 trials
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Oral rhabdomyosarcoma 0 trials
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Orbit rhabdomyosarcoma 0 trials
2 sub-types
- Orbit alveolar rhabdomyosarcoma 0 trials
- Orbit embryonal rhabdomyosarcoma 0 trials
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Ovary rhabdomyosarcoma 0 trials
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Prostate rhabdomyosarcoma 0 trials
1 sub-type
- Prostate embryonal rhabdomyosarcoma 0 trials
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Rectum rhabdomyosarcoma 0 trials
1 sub-type
- Anus rhabdomyosarcoma 0 trials
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Rhabdomyosarcoma of the cervix uteri 0 trials
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Rhabdomyosarcoma, embryonal, 2 0 trials
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Uterine corpus rhabdomyosarcoma 0 trials
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Vaginal rhabdomyosarcoma 0 trials
1 sub-type
Most studied deeper sub-types
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A pill that blocks RAS: can it help children whose tumors came back?
Disease control Not yet recruitingResearchers are testing daraxonrasib, an experimental pill that blocks RAS proteins, in children with solid tumors that have come back or stopped responding to treatment. The tumors include neuroblastoma and rhabdomyosarcoma, and all carry RAS mutations. The trial has two parts: …
Phase 1/2 • Sponsor: Children's Oncology Group • Aim: Disease control
Last updated Sep 17, 2026 00:00 UTC
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New hope for kids with tough cancers: drug combo trial launches
Disease control Not yet recruitingThis study tests a combination of chemotherapy drugs (liposomal irinotecan, vincristine, and temozolomide) with or without an additional drug (anlotinib) in children aged 3-18 whose solid tumors have returned or not responded to treatment. The goal is to see if this combination c…
Phase 2 • Sponsor: Tianjin Medical University Cancer Institute and Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Hope for rhabdomyosarcoma: vitamin a derivative joins chemo in new trial
Disease control Not yet recruitingThis Phase 2 trial tests whether adding all-trans retinoic acid (a vitamin A derivative) to standard VAC chemotherapy improves outcomes for 106 people aged 14-60 with intermediate-to-high-risk rhabdomyosarcoma, a rare muscle cancer. Participants will receive the drug combo in 21-…
Phase 2 • Sponsor: Fudan University • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Engineered immune cells take aim at Hard-to-Treat cancers
Disease control Not yet recruitingThis early-stage trial tests a new treatment for adults with solid tumors that have come back or not responded to standard therapy. The treatment uses a patient's own immune cells, modified in a lab to better recognize and attack cancer cells that carry a protein called GPC3. The…
Phase 1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Green dye could help surgeons spot hidden cancer in kids
Diagnosis Not yet recruitingThis study tests whether a green dye called indocyanine green (ICG) can help surgeons find sentinel lymph nodes—the first nodes where cancer might spread—in children with solid tumors. Ten children under 18 will get the dye injected during surgery, and doctors will check if it li…
Sponsor: University of Rochester • Aim: Diagnosis
Last updated Aug 28, 2026 00:00 UTC
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Light therapy may shield kids with cancer from chemo mouth sores
Prevention Not yet recruitingThis study tests whether light therapy (photobiomodulation) can prevent mouth sores in children receiving chemotherapy. Fifty children aged 0-30 will receive daily light treatments during hospital stays and at home. Researchers will check if the therapy is easy to use and accepta…
Sponsor: Medical College of Wisconsin • Aim: Prevention
Last updated Jun 27, 2026 14:01 UTC
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New app guides young cancer survivors through life after treatment
Knowledge-focused Not yet recruitingThis study is testing a mobile app called my.naviGATE for teens and young adults (ages 15-24) who have finished cancer treatment. The app provides personalized education, peer support, and tracks how patients are doing. Researchers want to see if the app helps patients feel more …
Sponsor: Dana-Farber Cancer Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC