Proteostasis deficiencies
MONDO:0021179Disorders caused by imbalances in the protein homeostasis network - synthesis, folding, and transport of proteins; post-translational modifications; and degradation or clearance of misfolded proteins.
Also known as: Proteostasis deficiency, Proteostasis dysfunction, Proteostasis dysfunctions, deficiencies, Proteostasis, deficiency, Proteostasis, dysfunction, Proteostasis, dysfunctions, Proteostasis, Misfolding disease, Protein
559 clinical trials for this condition and its sub-types, 1 tagged with Proteostasis deficiencies itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Proteostasis deficiencies
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Amyloidosis 133 trials · 322 incl. sub-types
12 sub-types
- AL amyloidosis 92 trials · 98 incl. sub-types Sub-types →
- Wild type ATTR amyloidosis 95 trials
- Hereditary amyloidosis 19 trials · 79 incl. sub-types Sub-types →
- ABeta2M amyloidosis 0 trials · 34 incl. sub-types Sub-types →
- Primary cutaneous amyloidosis 4 trials · 5 incl. sub-types Sub-types →
- AA amyloidosis 2 trials
- Soft tissue amyloid neoplasm 1 trial
- AApoAIV amyloidosis 0 trials
- AH amyloidosis 0 trials
- ALECT2 amyloidosis 0 trials
- Amyloidosis bronchopulmonary 0 trials
- Immunoglobulin heavy-and-light chain 0 trials
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Synucleinopathy 18 trials · 237 incl. sub-types
2 sub-types
- Lewy body dementia 130 trials
- Multiple system atrophy 110 trials · 119 incl. sub-types Sub-types →
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TDP-43 proteinopathy 2 trials
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3 sub-types
Most studied deeper sub-types
Familial amyloid neuropathy
(52)
Wild type ABeta2M amyloidosis
(34)
Primary systemic amyloidosis
(22)
Pure autonomic failure
(18)
Cerebral amyloid angiopathy
(16)
Multiple system atrophy, parkinsonian type
(12)
ATTRV122I amyloidosis
(7)
Alzheimer disease type 1
(4)
ATTRV30M amyloidosis
(4)
Multiple system atrophy, cerebellar type
(3)
Lichen amyloidosis
(2)
ABeta amyloidosis, dutch type
(1)
ACys amyloidosis
(1)
Familial primary localized cutaneous amyloidosis
(1)
Macular amyloidosis
(1)
AApoAI amyloidosis
(0)
ABetaA21G amyloidosis
(0)
ABeta amyloidosis, Arctic type
(0)
ABeta amyloidosis, Iowa type
(0)
ABeta amyloidosis, Italian type
(0)