Pleural mesothelioma

MONDO:0003308

A neoplasm that arises from the mesothelial cells of the pleura. The primary cause is exposure to asbestos. The major histologic variants are the epithelioid malignant mesothelioma, desmoplastic malignant mesothelioma, and sarcomatoid malignant mesothelioma. Patients present with persistent cough and shortness of breath.

Also known as: mesothelioma of pleura, mesothelioma of the pleura, pleura mesothelioma, pleural mesothelioma, pleural mesothelioma (disease), benign pleural mesothelioma, pleural mesothelioma (disease), benign

1517 clinical trials for this condition and its sub-types, 28 tagged with Pleural mesothelioma itself.

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Where it sits in the disease tree

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Part of

↑ Mesothelioma (179) ↑ Pleural neoplasm (97)

Sub-types of Pleural mesothelioma

Malignant pleural mesothelioma 71 trials · 75 incl. sub-types
2 sub-types
- Pleural epithelioid mesothelioma 8 trials
- Pleural sarcomatoid mesothelioma 2 trials
Pleural adenomatoid tumor 0 trials

Including sub-types (1517) Tagged with Pleural mesothelioma (28)

Trials to join now! 14 Not yet recruiting 1 Not yet finished but already full! 4 Completed 5 Terminated 4

Oral drug VT3989 takes on chemo in mesothelioma survival test

Disease control Not yet recruiting

Researchers are comparing an experimental oral drug called VT3989 with standard chemotherapy drugs gemcitabine or vinorelbine in adults with advanced epithelioid pleural mesothelioma. All participants have already received platinum-based chemotherapy and immunotherapy, and their …

Phase 3 • Sponsor: Vivace Therapeutics, Inc • Aim: Disease control

Last updated Sep 19, 2026 00:00 UTC

Pleural mesothelioma

Where it sits in the disease tree

Oral drug VT3989 takes on chemo in mesothelioma survival test