Nongerminomatous germ cell tumor
MONDO:0021656A term that refers to teratoma, embryonal carcinoma, yolk sac tumor, choriocarcinoma, or mixed forms of these tumors.
Also known as: Nongerminomatous germ cell tumor, Nongerminomatous germ cell tumor Including central nervous system, Nongerminomatous germ cell tumour, Nongerminomatous germ cell tumour Including central nervous system, non-dysgerminomatous germ cell tumor, non-dysgerminomatous germ cell tumour, non-germinomatous germ cell tumor, non-germinomatous germ cell tumour
1464 clinical trials for this condition and its sub-types, 12 tagged with Nongerminomatous germ cell tumor itself.
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Sub-types of Nongerminomatous germ cell tumor
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Extragonadal non-dysgerminomatous germ cell tumor 0 trials · 21 incl. sub-types
4 sub-types
- Extragonadal nonseminomatous germ cell tumor 5 trials · 19 incl. sub-types Sub-types →
- Central nervous system nongerminomatous germ cell tumor 2 trials Sub-types →
- Extragonadal teratoma 0 trials · 1 incl. sub-types Sub-types →
- Mediastinum teratoma 1 trial Sub-types →
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Teratoma 6 trials · 10 incl. sub-types
13 sub-types
- Gonadal teratoma 0 trials · 3 incl. sub-types Sub-types →
- Malignant teratoma 1 trial · 3 incl. sub-types Sub-types →
- Immature teratoma 2 trials Sub-types →
- Sacrococcygeal teratoma 2 trials
- Central nervous system teratoma 0 trials · 1 incl. sub-types Sub-types →
- Cystic teratoma 0 trials · 1 incl. sub-types Sub-types →
- Mature teratoma 0 trials · 1 incl. sub-types Sub-types →
- Mediastinum teratoma 1 trial Sub-types →
- Adult teratoma 0 trials Sub-types →
- Fallopian tube teratoma 0 trials
- Gastric teratoma 0 trials Sub-types →
- Nasopharyngeal teratoma 0 trials
- Teratoma with malignant transformation 0 trials Sub-types →
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Malignant non-dysgerminomatous germ cell tumor of ovary 1 trial · 2 incl. sub-types
5 sub-types
- Immature ovarian teratoma 1 trial · 2 incl. sub-types Sub-types →
- Ovarian embryonal carcinoma 1 trial Sub-types →
- Ovarian yolk sac tumor 1 trial Sub-types →
- Gestational ovarian choriocarcinoma 0 trials
- Polyembryoma of the ovary 0 trials
Most studied deeper sub-types
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Immunotherapy duo takes on resistant germ cell tumors
Disease control OngoingThis phase 2 trial tests two immunotherapy drugs, durvalumab and tremelimumab, in 30 adults with relapsed or refractory germ cell tumors. The goal is to see if the combination can shrink tumors or lower tumor markers. Participants must have measurable disease and have progressed …
Phase 2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Sep 20, 2026 00:00 UTC
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High-Dose chemo with stem cell transplant tested against standard therapy for tough germ cell cancers
Disease control OngoingThis phase 3 trial compares two chemotherapy approaches for people with germ cell tumors that have returned or not responded to initial treatment. One group receives standard-dose chemotherapy with paclitaxel, ifosfamide, and cisplatin (TIP). The other receives high-dose chemothe…
Phase 3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New hope for incurable germ cell tumors? cabozantinib trial underway
Disease control OngoingThis phase II trial is testing the drug cabozantinib in 50 patients with germ cell tumors that have not responded to standard chemotherapy. The goal is to see if the drug can stop or slow tumor growth. Patients take cabozantinib daily until the disease worsens or side effects bec…
Phase 2 • Sponsor: Jennifer King • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC