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Neurodevelopmental disorder with cerebellar atrophy and motor dysfunction

MONDO:0859152

A neurodevelopmental disorder caused by variation in the GEMIN5 gene, characterized by global developmental delay with prominent motor abnormalities, mainly axial hypotonia, gait ataxia, and appendicular spasticity.

Also known as: GEMIN5 disorder, GEMIN5-related neurodevelopmental disorder, NEDCAM

1 clinical trial for this condition and its sub-types.

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Broader categories

Disease (647) Nervous system disorder (225) Hereditary disease (176) Neurodevelopmental disorder (133) Human disease (14) Hereditary neurological disease (6) Disease of genetic or genomic mechanism (2) Disease by body system or component (0) Disease by etiologic mechanism (0) Mendelian neurodevelopmental disorder (0)
Trials to join now! 1
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  • Scientists track rare genetic disorder to map its hidden trajectory

    Knowledge-focused Recruiting now

    This study aims to better understand GEMIN5-related neurodevelopmental disorder, an ultra-rare genetic condition. Researchers will review medical records and follow participants over time to track developmental milestones, brain changes, vision, hearing, and survival. The goal is…

    Sponsor: University of Pittsburgh • Aim: Knowledge-focused

    Last updated Jul 11, 2026 00:00 UTC

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