Multiple endocrine neoplasia type 2

MONDO:0019003

Multiple endocrine neoplasia type 2 (MEN2) is a multiple endocrine neoplasia, a polyglandular cancer syndrome characterized by the occurrence of medullary thyroid carcinoma (MTC), pheochromocytoma (PCC), in one variant, primary hyperparathyroidism (PHPT). There are three forms: MEN2A, MEN2B, and familial medullary thyroid carcinoma (FMTC).

Also known as: MEN2, multiple endocrine neoplasia type 2

2808 clinical trials for this condition and its sub-types, 4 tagged with Multiple endocrine neoplasia type 2 itself.

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Where it sits in the disease tree

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Part of

↑ Thyroid gland carcinoma (237) ↑ Multiple endocrine neoplasia (62)

Sub-types of Multiple endocrine neoplasia type 2

Familial medullary thyroid carcinoma 23 trials
Multiple endocrine neoplasia type 2A 4 trials
Multiple endocrine neoplasia type 2B 2 trials

Including sub-types (2808) Tagged with Multiple endocrine neoplasia type 2 (4)

Trials to join now! 1 Not yet finished but already full! 2 Completed 1

New pill targets Hard-to-Treat cancers after other drugs fail

Disease control Completed

This early-stage trial is testing an oral drug called LOXO-260 in about 70 people with advanced cancers that have a specific change in the RET gene. The cancers have stopped responding to other targeted treatments. The study aims to find the safest dose and see if the drug can sh…

Phase 1 • Sponsor: Eli Lilly and Company • Aim: Disease control

Last updated Aug 23, 2026 00:00 UTC

Multiple endocrine neoplasia type 2

Where it sits in the disease tree

New pill targets Hard-to-Treat cancers after other drugs fail