Lip and oral cavity squamous cell carcinoma
MONDO:0044710A squamous cell carcinoma arising from the lip or the oral cavity. The oral cavity squamous cell carcinoma usually arises from the buccal mucosa, tongue, or gums. It occurs predominantly in adults who use tobacco and alcohol and has a tendency to metastasize early to lymph nodes.
Also known as: lip and oral cavity squamous cell cancer, lip and oral cavity squamous cell carcinoma, lip/oral cavity squam. cell car., squamous cell carcinoma of oral cavity and lip
3004 clinical trials for this condition and its sub-types, 21 tagged with Lip and oral cavity squamous cell carcinoma itself.
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Sub-types of Lip and oral cavity squamous cell carcinoma
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Oral cavity squamous cell carcinoma 141 trials · 156 incl. sub-types
7 sub-types
- Tongue squamous cell carcinoma 9 trials · 13 incl. sub-types Sub-types →
- Salivary gland squamous cell carcinoma 4 trials Sub-types →
- Verrucous carcinoma of oral cavity 3 trials
- Squamous cell carcinoma of buccal mucosa 2 trials
- Squamous cell carcinoma of floor of mouth 2 trials
- Squamous cell carcinoma of lip 2 trials
- Maxillary sinus squamous cell carcinoma 1 trial
Most studied deeper sub-types
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New combo therapy shows promise for Tough-to-Treat head and neck cancer
Disease control CompletedThis study tested whether giving the immunotherapy drug durvalumab alongside radiation works better than the standard cetuximab plus radiation for people with advanced head and neck cancer who cannot take the usual chemotherapy drug cisplatin. A total of 196 adults took part. The…
Phase 2/3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Aug 29, 2026 00:00 UTC
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New combo therapy shows promise for tough head and neck cancers
Disease control CompletedThis phase II trial tested whether adding sorafenib to cetuximab works better than cetuximab alone for patients with advanced head and neck cancer that has come back or spread. Fifty-five adults with various types of head and neck cancer took part. The study measured how long pat…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC