Kidney Wilms tumor

This phase 3 trial tested how well combination chemotherapy with or without radiation therapy works in 395 children and young adults with newly diagnosed stage III or IV Wilms tumor. The goal was to see if adding radiation could improve the chance of staying cancer-free for 4 yea…

This study tested giving chemotherapy before surgery to children with Wilms tumor, a rare kidney cancer. The goal was to shrink tumors so surgeons could remove less kidney tissue, helping preserve kidney function. 249 children took part, and the approach aimed to reduce the need …

This phase 3 trial studied how well chemotherapy with or without radiation works after surgery for children with a type of kidney cancer called Wilms tumor. Over 800 children with low- or standard-risk disease took part. The goal was to see if less intensive treatment could still…

This completed research study collected and stored tumor tissue, blood, and urine samples from 8,000 children and young adults with kidney tumors. The goal was to help scientists study DNA changes and find biomarkers that could improve understanding of these cancers. No treatment…

This study looked back at 72 children treated for Wilms tumor (a kidney cancer) that had spread into the vena cava, the large vein carrying blood to the heart. Researchers reviewed medical records from 1999 to 2019 to understand how surgery was managed and what complications occu…