Intraepithelial neoplasia

MONDO:0024474

A precancerous neoplastic process that affects the squamous, glandular, or transitional cell epithelium without evidence of invasion. According to the degree of nuclear atypia, number of mitotic figures, and presence of architectural distortion, it is classified as low grade (mild dysplasia) or high grade (moderate or severe dysplasia).

Also known as: epithelial dysplasia, intraepithelial neoplasia, intraepithelial neoplasm

1514 clinical trials for this condition and its sub-types, 25 tagged with Intraepithelial neoplasia itself.

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Where it sits in the disease tree

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Part of

↑ Epithelial neoplasm (15072) ↑ Precancerous condition (518)

Sub-types of Intraepithelial neoplasia

Squamous cell intraepithelial neoplasia 26 trials · 43 incl. sub-types
3 sub-types
- Cervical squamous intraepithelial neoplasia 28 trials
- Conjunctival intraepithelial neoplasm 0 trials
- Corneal intraepithelial neoplasm 0 trials
Prostate intraepithelial neoplasia 2 trials
1 sub-type
- Grade III prostatic intraepithelial neoplasia 0 trials
Small intestinal intraepithelial neoplasia 1 trial

Including sub-types (1514) Tagged with Intraepithelial neoplasia (25)

Trials to join now! 10 Not yet recruiting 5 Not yet finished but already full! 3 Completed 6 Terminated 1

Glow-in-the-Dark dye could help surgeons spot hidden oral cancer cells

Diagnosis Stopped early

This study tested a dye called tozuleristide that makes oral cancer cells glow under special light during surgery. The goal was to help surgeons see and remove all cancer while sparing healthy tissue. The trial included 8 adults with oral cavity cancer or high-grade dysplasia. Th…

Phase 1/2 • Sponsor: University of Washington • Aim: Diagnosis

Last updated Sep 18, 2026 00:00 UTC

Intraepithelial neoplasia

Where it sits in the disease tree

Glow-in-the-Dark dye could help surgeons spot hidden oral cancer cells