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Infantile myofibromatosis

MONDO:0016824

A benign, multifocal, nodular and well-circumscribed neoplasm usually seen as a congenital neoplasm or in the first year of life. It is characterized by a biphasic growth pattern and is composed of small, undifferentiated mesenchymal cells associated with branching thin-walled vessels and more mature neoplastic spindle cells with abundant eosinophilic cytoplasm in a collagenous stroma.

Also known as: infantile hemangiopericytoma, infantile myofibromatosis, multicentric myofibromatosis, myofibromatosis, IMS

1441 clinical trials for this condition and its sub-types, 1 tagged with Infantile myofibromatosis itself.

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Where it sits in the disease tree

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Part of

↑ Hereditary disorder of connective tissue (1311) ↑ Benign perivascular tumor (18) ↑ Benign soft tissue neoplasm (16)

Sub-types of Infantile myofibromatosis

Myofibromatosis, infantile, 1 0 trials
Myofibromatosis, infantile, 2 0 trials

Including sub-types (1441) Tagged with Infantile myofibromatosis (1)

Not yet finished but already full! 1

New oral drug shows promise for kids with rare RET-Driven cancers

Disease control Ongoing

This study tests an oral drug called selpercatinib (LOXO-292) in children with advanced solid or brain tumors that have a specific RET gene change. The trial has two parts: first finding a safe dose, then measuring how many children's tumors shrink. About 36 children whose cancer…

Phase 1/2 • Sponsor: Eli Lilly and Company • Aim: Disease control

Last updated Jun 27, 2026 08:09 UTC

Infantile myofibromatosis

Where it sits in the disease tree

New oral drug shows promise for kids with rare RET-Driven cancers