Indolent systemic mastocytosis

MONDO:0020331

Indolent systemic mastocytosis (ISM) is a benign form of systemic mastocytosis (SM) characterized by an abnormal proliferation of mast cells either only in bone marrow or in numerous tissues.

Also known as: ISM, indolent systemic mastocytosis (morphologic abnormality), ism

1854 clinical trials for this condition and its sub-types, 8 tagged with Indolent systemic mastocytosis itself.

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Where it sits in the disease tree

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↑ Systemic mastocytosis (24)

Sub-types of Indolent systemic mastocytosis

Smouldering systemic mastocytosis 3 trials
Isolated bone marrow mastocytosis 2 trials

Including sub-types (1854) Tagged with Indolent systemic mastocytosis (8)

Trials to join now! 5 Not yet recruiting 1 Not yet finished but already full! 2

Can biological signals explain mastocytosis symptoms?

Knowledge-focused Not yet recruiting

This study aims to understand how symptoms of indolent systemic mastocytosis relate to biological signals in the body. Researchers will collect samples and data from 25 participants over 12 weeks to see how different treatments affect these signals. The goal is to improve underst…

Sponsor: Mayo Clinic • Aim: Knowledge-focused

Last updated Aug 20, 2026 00:00 UTC

Indolent systemic mastocytosis

Where it sits in the disease tree

Can biological signals explain mastocytosis symptoms?