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Impaired renal function disease
MONDO:0001343Any disease in which the causes of the disease is a perturbation of the kidney leading to its dysfunction.
Also known as: disease of kidney, kidney disease
129 clinical trials for this condition and its sub-types, 109 tagged with Impaired renal function disease itself.
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Sub-types of Impaired renal function disease
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Secondary hyperparathyroidism of renal origin 7 trials · 18 incl. sub-types
1 sub-type
- Renal osteodystrophy 12 trials
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Nephrogenic diabetes insipidus 1 trial · 2 incl. sub-types
2 sub-types
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Heart-Kidney drug trial halted early – what happened?
Disease control Stopped earlyThis early-stage trial tested an experimental drug called AZD3427 in 10 people with heart failure and reduced kidney function. The goal was to see if the drug could improve blood flow to the kidneys, measured with a special PET scan. However, the study was terminated early, so we…
Phase 1 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Insulin showdown: toujeo vs tresiba for diabetics with kidney disease
Disease control Stopped earlyThis study compared two long-acting insulins, Toujeo and Tresiba, in people with type 2 diabetes who also have kidney problems and had never used insulin before. The goal was to see which one controls blood sugar better and causes fewer low blood sugar events. The trial was stopp…
Phase 4 • Sponsor: Sanofi • Aim: Disease control
Last updated Jun 26, 2026 14:43 UTC
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Scientists hunt for early warning signs of kidney failure
Knowledge-focused Stopped earlyThis study aimed to find substances in blood and urine that could signal kidney damage earlier than current tests. Researchers compared samples from healthy volunteers, people with low fluid levels, those at high risk for kidney failure, and patients with acute kidney failure. Th…
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC