Hemolytic anemia
MONDO:0003664Anemia resulting from the premature destruction of the peripheral blood red cells. It may be congenital or it may be caused by infections, medications, or malignancies.
Also known as: anaemia hemolytic, anemia hemolytic, anemia, hemolytic, hemolytic anemia
188 clinical trials for this condition and its sub-types, 19 tagged with Hemolytic anemia itself.
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Sub-types of Hemolytic anemia
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Paroxysmal nocturnal hemoglobinuria 73 trials
2 sub-types
- Paroxysmal nocturnal hemoglobinuria 1 0 trials
- Paroxysmal nocturnal hemoglobinuria 2 0 trials
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Autoimmune hemolytic anemia 49 trials · 72 incl. sub-types
7 sub-types
- Autoimmune hemolytic anemia, warm type 29 trials
- Evans syndrome 19 trials
- Autoimmune hemolytic anemia, cold type 2 trials · 15 incl. sub-types Sub-types →
- Mixed-type autoimmune hemolytic anemia 1 trial
- Drug-induced autoimmune hemolytic anemia 0 trials
- Giant cell hepatitis with autoimmune hemolytic anemia 0 trials
- Neonatal autoimmune hemolytic anemia 0 trials
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Familial hemolytic anemia 4 trials · 27 incl. sub-types
23 sub-types
- Congenital nonspherocytic hemolytic anemia 1 trial · 12 incl. sub-types Sub-types →
- Congenital dyserythropoietic anemia 4 trials · 5 incl. sub-types Sub-types →
- Abetalipoproteinemia 2 trials
- Cutaneous porphyria 2 trials
- Hereditary spherocytosis 2 trials Sub-types →
- Southeast Asian ovalocytosis 2 trials
- Glycogen storage disease VII 1 trial
- Glycogen storage disease due to aldolase A deficiency 1 trial
- Rh deficiency syndrome 0 trials
- X-linked congenital hemolytic anemia 0 trials
- Cryohydrocytosis 0 trials
- Dehydrated hereditary stomatocytosis 2 0 trials
- Dehydrated hereditary stomatocytosis with or without pseudohyperkalemia and/or perinatal edema 0 trials
- Elliptocytosis 1 0 trials
- Elliptocytosis 2 0 trials
- Familial pseudohyperkalemia 0 trials
- Hemolytic anemia due to diphosphoglycerate mutase deficiency 0 trials
- Hemolytic disease of fetus and newborn, RH-induced 0 trials
- Hereditary cryohydrocytosis with reduced stomatin 0 trials
- Overhydrated hereditary stomatocytosis 0 trials
- Primary CD59 deficiency 0 trials
- Renal tubular acidosis, distal, 4, with hemolytic anemia 0 trials
- Triosephosphate isomerase deficiency 0 trials
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Hereditary stomatocytosis 1 trial · 3 incl. sub-types
7 sub-types
- Southeast Asian ovalocytosis 2 trials
- Rh deficiency syndrome 0 trials
- Cryohydrocytosis 0 trials
- Dehydrated hereditary stomatocytosis 0 trials Sub-types →
- Familial pseudohyperkalemia 0 trials
- Hereditary cryohydrocytosis with reduced stomatin 0 trials
- Overhydrated hereditary stomatocytosis 0 trials
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Hereditary elliptocytosis 0 trials · 2 incl. sub-types
5 sub-types
- Southeast Asian ovalocytosis 2 trials
- Elliptocytosis 1 0 trials
- Elliptocytosis 2 0 trials
- Elliptocytosis 3 0 trials
- Hemolytic anemia with thermal sensitivity of red cells 0 trials
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Non-autoimmune hemolytic anemia 1 trial
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Heinz body anemia 0 trials
Most studied deeper sub-types
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Can a new drug calm the immune System's attack on blood cells?
Disease control CompletedThis study is testing an experimental drug called povetacicept in adults with autoimmune cytopenias — conditions where the immune system mistakenly destroys blood cells, leading to low platelet counts (immune thrombocytopenia) or anemia (autoimmune hemolytic anemia and cold agglu…
Phase 1/2 • Sponsor: Alpine Immune Sciences Inc, A Subsidiary of Vertex • Aim: Disease control
Last updated Sep 16, 2026 00:00 UTC
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Promising new drug shows hope for rare anemia patients
Disease control CompletedThis study tested a drug called mitapivat (AG-348) in 52 adults with pyruvate kinase deficiency, a rare genetic condition that causes red blood cells to break down too quickly, leading to anemia. The goal was to see if different doses of the drug are safe and help control the dis…
Phase 2 • Sponsor: Agios Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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New pill could cut blood transfusions for blood disorders
Disease control CompletedThis Phase 2 study tested an experimental drug called etavopivat in 53 people with thalassemia or sickle cell disease. The goal was to see if the pill could safely reduce the number of red blood cell transfusions needed and raise hemoglobin levels. Participants took 400 mg of eta…
Phase 2 • Sponsor: Forma Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Gene therapy offers hope for rare blood disorder
Disease control CompletedThis phase 1 trial tested a gene therapy called RP-L301 in 4 people with pyruvate kinase deficiency, a rare inherited blood disorder that causes severe anemia and often requires frequent blood transfusions. The treatment uses the patient's own blood stem cells, which are modified…
Phase 1 • Sponsor: Rocket Pharmaceuticals Inc. • Aim: Disease control
Last updated Jun 26, 2026 13:53 UTC
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Could carbon monoxide be a medicine? new trial for sickle cell
Symptom relief CompletedThis study tests a new liquid drug called HBI-002, which contains carbon monoxide, in 9 people with sickle cell disease aged 14 to 55. Participants take the drug daily for 14 days to see if it is safe and helps with symptoms. The goal is to find a better way to manage this painfu…
Phase 2 • Sponsor: Hillhurst Biopharmaceuticals, Inc. • Aim: Symptom relief
Last updated Aug 08, 2026 00:03 UTC