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Generalized resistance to thyroid hormone

MONDO:0009043

A thyroid hormone resistance syndrome characterized by resistance in the pituitary gland and in most or all of the peripheral tissues.

Also known as: GRTH, Refetoff syndrome, deafness-thyroid hormone resistance syndrome

2 clinical trials for this condition and its sub-types, 1 tagged with Generalized resistance to thyroid hormone itself.

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Where it sits in the disease tree

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Part of

↑ Hyperthyroidism (70) ↑ Thyroid hormone resistance syndrome (4)

Sub-types of Generalized resistance to thyroid hormone

Thyroid hormone resistance, generalized, autosomal dominant 2 trials
Athyreosis 0 trials
Thyroid ectopia 0 trials
Thyroid hemiagenesis 0 trials
Thyroid hormone resistance, generalized, autosomal recessive 0 trials
Thyroid hypoplasia 0 trials

Including sub-types (2) Tagged with Generalized resistance to thyroid hormone (1)

Trials to join now! 1

New study aims to unlock mysteries of rare thyroid condition

Knowledge-focused Recruiting now

This observational study will enroll 150 people to better understand thyroid hormone resistance syndromes, rare conditions where the body does not respond properly to thyroid hormone. Researchers will use genetic testing, blood analysis, and lab-grown cells to find better ways to…

Sponsor: Istituto Auxologico Italiano • Aim: Knowledge-focused

Last updated Jun 26, 2026 12:55 UTC