Facial hemiatrophy
MONDO:0007710Progressive hemifacial atrophy (PHA) is a rare acquired disorder, characterized by unilateral slowly progressive atrophy of the skin and soft tissues of half of the face leading to a sunken appearance. Muscles, cartilage and the underlying bony structures may also be involved.
Also known as: Romberg syndrome, hemifacial atrophy, parry-Romberg syndrome, progressive facial hemiatrophy, progressive hemifacial atrophy, HFA, PHA, Romberg hemi-facial atrophy
2 clinical trials for this condition and its sub-types.
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Can a cream restore youthful skin? new trial says maybe.
Symptom relief CompletedThis study tested a skin cream designed to improve skin elasticity and volume in 35 healthy adults with signs of facial aging. Participants applied the cream and were measured for changes in skin firmness and fullness. The goal was to see if the cream could help reduce the effect…
Phase: NA • Sponsor: Adipeau Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 13:01 UTC
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Study uses 3D scans to see how well surgery fixes facial asymmetry
Knowledge-focused CompletedHemifacial atrophy causes one side of the face to shrink, creating an uneven appearance. Surgeons often use fat grafting or free flap reconstruction to restore volume, but it's not clear how much symmetry actually improves. This study looks back at 60 patients treated between 202…
Sponsor: Peking Union Medical College • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC