Endogenous Cushing syndrome

MONDO:0957431

Any Cushing syndrome caused by body's prolonged overproduction of cortisol that can be dependent on or independent of adrenocorticotropic hormone (ACTH).

Also known as: endogenous CS

40 clinical trials for this condition and its sub-types, 3 tagged with Endogenous Cushing syndrome itself.

Follow this condition to get notified about new trials

Where it sits in the disease tree

Browse by category →

Part of

↑ Adrenal gland disorder (354) ↑ Cushing syndrome (66)

Sub-types of Endogenous Cushing syndrome

ACTH-dependent Cushing syndrome 23 trials · 26 incl. sub-types
2 sub-types
- Cushing disease due to pituitary adenoma 23 trials
- Ectopic Cushing syndrome 1 trial
ACTH-independent Cushing syndrome 9 trials · 11 incl. sub-types
3 sub-types

Most studied deeper sub-types

ACTH-independent macronodular adrenal hyperplasia 1 (0) ACTH-independent macronodular adrenal hyperplasia 2 (0) ACTH-independent macronodular adrenal hyperplasia 3 (0)

Including sub-types (40) Tagged with Endogenous Cushing syndrome (3)

Trials to join now! 1 Not yet finished but already full! 2

Can a steroid Add-On make cushing syndrome treatment safer?

Disease control Recruiting now

Researchers are testing a block-and-replace strategy for people with endogenous Cushing syndrome, a condition where the body makes too much cortisol. Participants receive osilodrostat, a drug that lowers cortisol production, along with a replacement glucocorticoid called methylpr…

Sponsor: University of Michigan • Aim: Disease control

Last updated Sep 11, 2026 00:00 UTC

Endogenous Cushing syndrome

Where it sits in the disease tree

Most studied deeper sub-types

Can a steroid Add-On make cushing syndrome treatment safer?