Dermatofibrosarcoma protuberans

MONDO:0011934

Dermatofibrosarcoma protuberans (DFSP) is a rare infiltrating soft tissue sarcoma, generally of low grade malignancy, arising from the dermis of the skin and characteristically associated with a specific chromosomal translocation t(17;22).

Also known as: DFSP, dermatofibrosarcoma, dermatofibrosarcoma protuberans, familial dermatofibrosarcoma protuberans (subtype), giant cell fibroblastoma, metastatic dermatofibrosarcoma protuberans (subtype)

2829 clinical trials for this condition and its sub-types, 11 tagged with Dermatofibrosarcoma protuberans itself.

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Where it sits in the disease tree

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Part of

↑ Integumentary system cancer (1088) ↑ Fibrosarcoma (21)

Sub-types of Dermatofibrosarcoma protuberans

Pigmented dermatofibrosarcoma protuberans 0 trials

Including sub-types (2829) Tagged with Dermatofibrosarcoma protuberans (11)

Trials to join now! 6 Not yet recruiting 1 Not yet finished but already full! 1 Completed 3

New hope for rare skin cancer? drug cocktail targets resistant DFSP

Disease control Not yet recruiting

This phase 2 trial will test whether combining two newer drugs (toripalimab and anlotinib) with standard chemotherapy can shrink tumors in people with a rare skin cancer called dermatofibrosarcoma protuberans (DFSP) that has stopped responding to the usual treatment. The study pl…

Phase 2 • Sponsor: Yanjie Zhang, MD • Aim: Disease control

Last updated Jun 27, 2026 14:00 UTC

Dermatofibrosarcoma protuberans

Where it sits in the disease tree

New hope for rare skin cancer? drug cocktail targets resistant DFSP