Congenital velopharyngeal incompetence
MONDO:0008180Failure of the soft palate to reach the posterior pharyngeal wall to close the opening between the oral and nasal cavities. Incomplete velopharyngeal closure is primarily related to surgeries (adenoidectomy; cleft palate) or an incompetent palatopharyngeal sphincter. It is characterized by hypernasal speech.
Also known as: palatopharyngeal incompetence, velopharyngeal incompetence, velopharyngeal insufficiency
6 clinical trials for this condition and its sub-types.
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Could a simple breathing device help children speak more clearly without surgery?
Disease control Recruiting nowThis study tests whether a handheld device that strengthens the muscles used for breathing and swallowing can improve speech in children aged 5 to 17 with velopharyngeal dysfunction, a condition where the soft palate does not close properly, causing nasal-sounding speech. Partici…
Sponsor: Noel Jabbour • Aim: Disease control
Last updated Jul 22, 2026 00:00 UTC
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Throat plumping injection could give cancer survivors their voice back
Symptom relief Recruiting nowSome head and neck cancer survivors develop velopharyngeal dysfunction (VPD), where the soft palate doesn't close properly, causing nasal-sounding speech and trouble swallowing. This study tests a simple injection that plumps up the back of the throat to improve closure. Research…
Sponsor: Vanessa Torrecillas • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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MRI scans reveal hidden causes of speech issues in cleft palate kids
Knowledge-focused Recruiting nowThis study investigates why some children still have speech problems (velopharyngeal insufficiency) after cleft palate surgery. Researchers will use real-time MRI to look at how the soft palate moves and its muscle structure in children aged 7 to 12. By comparing children with di…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC