Congenital heart malformation
MONDO:0019512A disease that has its basis in the disruption of heart development.
Also known as: congenital heart malformation, disorder of heart development, heart development disease, congenital non-syndromic heart malformation, rare congenital non-syndromic heart malformation
155 clinical trials for this condition and its sub-types, 3 tagged with Congenital heart malformation itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Congenital heart malformation
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Congenital anomaly of the great arteries 1 trial · 72 incl. sub-types
15 sub-types
- Aortic arch defects 1 trial · 28 incl. sub-types Sub-types →
- Aneurysm or dilatation of ascending aorta 27 trials
- Congenital pulmonary valve stenosis 2 trials · 7 incl. sub-types Sub-types →
- Pulmonary branch stenosis 5 trials
- Congenital pulmonary veins atresia or stenosis 4 trials Sub-types →
- Absence of the pulmonary artery 1 trial
- Aortic arch interruption 0 trials
- Aorto-ventricular tunnel 0 trials Sub-types →
- Congenital patent ductus arteriosus aneurysm 0 trials
- Fixed subaortic stenosis 0 trials Sub-types →
- Idiopathic pulmonary artery dilatation 0 trials
- Premature closure of the arterial duct 0 trials
- Primary pulmonary vein stenosis 0 trials
- Pulmonary artery hypoplasia 0 trials
- Scimitar syndrome 0 trials
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Conotruncal heart malformations 1 trial · 41 incl. sub-types
8 sub-types
- Tetralogy of fallot 34 trials
- Persistent truncus arteriosus 8 trials Sub-types →
- Double outlet right ventricle 2 trials · 3 incl. sub-types Sub-types →
- Pulmonary atresia with ventricular septal defect 1 trial
- Abnormal origin of the pulmonary artery 0 trials Sub-types →
- Congenital aortopulmonary window 0 trials
- Double outlet left ventricle 0 trials
- Pulmonary valve agenesis 0 trials Sub-types →
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Univentricular cardiopathy 14 trials · 38 incl. sub-types
3 sub-types
- Univentricular heart 22 trials Sub-types →
- Hypoplastic left heart syndrome 10 trials Sub-types →
- Hypoplastic right heart syndrome 0 trials · 4 incl. sub-types Sub-types →
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Transposition of the great arteries 10 trials · 11 incl. sub-types
3 sub-types
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Congenital left-sided heart lesions 0 trials · 10 incl. sub-types
1 sub-type
- Hypoplastic left heart syndrome 10 trials Sub-types →
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Coronary artery congenital malformation 3 trials · 4 incl. sub-types
9 sub-types
- Aortopulmonary coronary arterial course 1 trial
- Stenosis or atrophy of the coronary ostium 1 trial
- Abnormal number of coronary ostia 0 trials
- Anomalous left coronary artery from the pulmonary artery 0 trials
- Congenital coronary artery aneurysm 0 trials
- Coronary arterial fistulas 0 trials
- Coronary artery intramyocardial course 0 trials
- Intramural coronary arterial course 0 trials
- Malposition of the coronary ostium 0 trials
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Congenital mitral malformation 0 trials · 2 incl. sub-types
2 sub-types
- Congenital mitral valve insufficiency and/or stenosis 1 trial · 2 incl. sub-types Sub-types →
- Cleft mitral valve 0 trials Sub-types →
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Visceral heterotaxy 1 trial
19 sub-types
- Dextrocardia 1 trial
- Situs inversus 1 trial Sub-types →
- Heterotaxy, visceral, 1, X-linked 0 trials
- Heterotaxy, visceral, 10, autosomal, with male infertility 0 trials
- Heterotaxy, visceral, 11, autosomal, with male infertility 0 trials
- Heterotaxy, visceral, 12, autosomal 0 trials
- Heterotaxy, visceral, 13, autosomal 0 trials
- Heterotaxy, visceral, 14, autosomal 0 trials
- Heterotaxy, visceral, 2, autosomal 0 trials
- Heterotaxy, visceral, 3, autosomal 0 trials
- Heterotaxy, visceral, 4, autosomal 0 trials
- Heterotaxy, visceral, 5, autosomal 0 trials
- Heterotaxy, visceral, 6, autosomal 0 trials
- Heterotaxy, visceral, 7, autosomal 0 trials
- Heterotaxy, visceral, 8, autosomal 0 trials
- Heterotaxy, visceral, 9, autosomal, with male infertility 0 trials
- Laterality defects, autosomal dominant 0 trials
- Levocardia 0 trials
- Right atrial isomerism 0 trials
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Laubry-Pezzi syndrome 0 trials
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Atrial septal aneurysm 0 trials
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Cardiac diverticulum 0 trials
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Congenital Gerbode defect 0 trials
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Congenital acardia 0 trials
1 sub-type
- Holoacardius amorphus 0 trials
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Congenital pericardium anomaly 0 trials
3 sub-types
- Congenital complete agenesis of pericardium 0 trials
- Congenital partial agenesis of pericardium 0 trials
- Pleuro-pericardial cyst 0 trials
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Congenital right-sided heart lesions 0 trials
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Criss-cross heart 0 trials
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Ectasia of the left appendage 0 trials
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Ectopia cordis 0 trials
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Interventricular septum aneurysm 0 trials
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Mesocardia 0 trials
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Triatrial heart 0 trials
2 sub-types
- Cor triatriatum dexter 0 trials
- Cor triatriatum sinister 0 trials
Most studied deeper sub-types
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New heart solution tested in Kids' surgery: could it offer better protection?
Disease control PausedThis study compares two solutions, Custodiol and Custodiol-N, used to protect the heart during surgery for children with congenital heart defects. About 100 children will receive one of the two solutions while on a heart-lung machine. The goal is to see which one is safer and bet…
Phase 2 • Sponsor: Dr. F. Köhler Chemie GmbH • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Gas during heart surgery may shield Babies' brains and kidneys
Disease control By invitation onlyThis study tests whether adding nitric oxide gas to the heart-lung machine during surgery can reduce damage to the brain and kidneys in infants under 1 year old with congenital heart disease. Researchers will measure specific proteins in the blood before and after surgery and mon…
Phase 2/3 • Sponsor: Vanderbilt University Medical Center • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC