Colorectal squamous cell carcinoma

MONDO:0006165

A very rare colorectal carcinoma characterized by the presence of a malignant squamous cell infiltrate.

Also known as: colorectal (colon or rectal) squamous cell cancer, colorectal squamous cell cancer, colorectal squamous cell carcinoma, colorectum squamous cell carcinoma

2933 clinical trials for this condition and its sub-types, 1 tagged with Colorectal squamous cell carcinoma itself.

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Where it sits in the disease tree

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Part of

↑ Squamous cell carcinoma (1766) ↑ Colorectal carcinoma (1166)

Sub-types of Colorectal squamous cell carcinoma

Squamous cell carcinoma of rectum 8 trials · 53 incl. sub-types
3 sub-types
- Anal squamous cell carcinoma 40 trials · 49 incl. sub-types Sub-types →
- Rectal adenosquamous carcinoma 0 trials
- Rectal cloacogenic carcinoma 0 trials
Colorectal adenosquamous carcinoma 0 trials
2 sub-types
- Adenosquamous colon carcinoma 0 trials
- Rectal adenosquamous carcinoma 0 trials
Squamous cell carcinoma of colon 0 trials
1 sub-type
- Adenosquamous colon carcinoma 0 trials

Most studied deeper sub-types

Anal canal squamous cell carcinoma (12) Anal margin squamous cell carcinoma (4) Anus basaloid carcinoma (3) Anal verrucous carcinoma (0)

Including sub-types (2933) Tagged with Colorectal squamous cell carcinoma (1)

Not yet finished but already full! 1

Immunotherapy duo takes on rare tumors

Disease control Ongoing

This phase 2 trial is testing a combination of two immunotherapy drugs, nivolumab and ipilimumab, in 798 people with over 50 types of rare cancers. The goal is to see if these drugs can shrink tumors by helping the immune system attack cancer cells. Participants receive the drugs…

Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control

Last updated Jun 27, 2026 14:00 UTC

Colorectal squamous cell carcinoma

Where it sits in the disease tree

Most studied deeper sub-types

Immunotherapy duo takes on rare tumors