Cure My Disease

Don't miss your cure!

Log in / Sign up

CHEK2-related cancer predisposition

MONDO:0700271

Hereditary cancer predisposition due to variation(s) in the CHEK2 gene. Pathogenic germline variation in CHEK2 confers an autosomal dominant predisposition to tumor formation at multiple primary sites, including breast cancer and prostate cancer.

39 clinical trials for this condition and its sub-types, 7 tagged with CHEK2-related cancer predisposition itself.

Follow this condition to get notified about new trials

Where it sits in the disease tree

Browse by category →

Part of

↑ Hereditary neoplastic syndrome (731)

Including sub-types (39) Tagged with CHEK2-related cancer predisposition (7)

Trials to join now! 2 Not yet recruiting 1 Not yet finished but already full! 2 Completed 1 Terminated 1

Can a Hormone-Binding protein predict breast cancer risk? trial tests tamoxifen and fasting

Prevention Completed

Researchers are testing whether low-dose tamoxifen or a 5:2 intermittent fasting diet can raise levels of a protein called sex hormone binding globulin (SHBG) in women at high risk of breast cancer. Higher SHBG levels have been linked to lower breast cancer risk. The trial enroll…

Phase 2 • Sponsor: European Institute of Oncology • Aim: Prevention

Last updated Sep 13, 2026 00:00 UTC