ALECT2 amyloidosis

MONDO:0018588

A rare, systemic amyloidosis characterized by slowly progressive renal disease presenting with proteinuria, hypertension and decreased glomerular filtration rate leading to progressive renal failure. Histology reveals amyloid deposits of leukocyte chemotactic factor-2 protein in the renal cortical interstitium, tubular basement membranes, glomeruli and the vessel walls. Extra-renal deposits can be seen in the liver, lungs, spleen and adrenal glands.

Also known as: LECT2 amyloidosis, leukocyte chemotactic factor-2 amyloidosis

3 clinical trials for this condition and its sub-types, 0 tagged with ALECT2 amyloidosis itself.

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