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137755 trials found · Page 6888 of 6888
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A phase III randomized, Double-Blind study of induction (Daunorubicin/Cytarabine) and consolidation (High-Dose cytarabine) chemotherapy + midostaurin (PKC412) (IND #101261) or placebo in newly diagnosed patients < 60 years of age with FLT3 mutated acute myeloid leukemia (AML)
CompletedThe purpose of this study is to compare the effects, good and/or bad, of a standard chemotherapy regimen for AML that includes the drugs daunorubicin and cytarabine combined with or without midostaurin (also known as PKC412), to find out which is better. This research is being do…
Phase 3 • Sponsor: Alliance for Clinical Trials in Oncology
Last updated Oct 23, 2026 00:00 UTC
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A phase i study of De-Immunized DI-Leu16-IL2 immunocytokine in patients with B-Cell Non-Hodgkin lymphoma
CompletedRATIONALE: Biological therapies, such as fusion protein cytokine therapy, may stimulate the immune system in different ways and stop cancer cells from growing. Monoclonal antibodies, such as rituximab, can block cancer growth in different ways. Some block the ability of cancer ce…
Phase 1 • Sponsor: City of Hope Medical Center
Last updated Oct 25, 2026 00:00 UTC
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Massive 5-Million person study reveals new insights about blood fats
OngoingCloser examination of granular lipid data in a large population offers numerous opportunities to generate new knowledge, ranging from studies examining concordance between commonly used lipid parameters to phenotypic characterization of rare or extreme disorders of lipid metaboli…
Sponsor: Johns Hopkins University
Last updated Nov 24, 2025 13:56 UTC
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A phase i trial of PS-341 in combination with topotecan in advanced solid tumor malignancies
CompletedRATIONALE: Bortezomib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Drugs used in chemotherapy, such as topotecan hydrochloride, work in different ways to stop the growth of tumor cells, either b…
Phase 1 • Sponsor: City of Hope Medical Center
Last updated Oct 24, 2026 00:00 UTC
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Effect of the consumption of a probiotic strain on the prevention of post-operative recurrence in Crohn's disease
CompletedA double-blind, multicentre, stratified by centre, randomised, parallel study with two groups of adult patients operated on for Crohn's disease, to determine if oral ingestion of probiotics could prevent the appearance of Crohn's disease recurrent endoscopic ileo-colonic lesions …
Sponsor: Danone Global Research & Innovation Center
Last updated Oct 23, 2026 00:00 UTC
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Maternal cancer diagnosis and treatment during pregnancy:a registry for maternal, fetal, and neonatal outcomes with longitudinal follow up of child development and maternal psychological well being
Recruiting nowThe objective of this study is to follow the treatment options offered to pregnant women diagnosed with cancer and study the impact that their treatment or delay of treatment has on their own health and that of their children.
Sponsor: The Cooper Health System
Last updated Oct 24, 2026 00:00 UTC
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Shanghai epidemiology study for adolescents and children with cancer
Recruiting nowThe purpose of this study is to describe the morbidity, mortality, disability and survival rate in Shanghai adolescents and children with cancer diagnosed since January 2002.
Sponsor: Children's Cancer Group, China
Last updated Oct 24, 2026 00:00 UTC
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Managed access programs for MAS825, arumakimig
Expanded access (paused)The purpose of this registration is to list Managed Access Programs (MAPs) related to MAS825, arumakimig
Sponsor: Novartis Pharmaceuticals
Last updated Oct 24, 2026 00:00 UTC
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[Trial of device that is not approved or cleared by the U.S. FDA]
Details not publishedSponsor: [Redacted]
Last updated Oct 25, 2026 00:00 UTC
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[Trial of device that is not approved or cleared by the U.S. FDA]
Details not publishedSponsor: [Redacted]
Last updated Oct 25, 2026 00:00 UTC
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[Trial of device that is not approved or cleared by the U.S. FDA]
Details not publishedSponsor: [Redacted]
Last updated Oct 23, 2026 00:00 UTC
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New hope for advanced breast cancer patients with specific gene mutation
Disease control Expanded accessThe purpose of this Cohort Treatment Plan is to allow access to alpelisib for patients diagnosed with HR-positive, HER2-negative advanced breast cancer with mutated phosphoinositide 3-kinase who progressed on or after AI treatment. The patient's Treating Physician should follow t…
Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jan 13, 2026 15:13 UTC
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[Trial of device that is not approved or cleared by the U.S. FDA]
Details not publishedSponsor: [Redacted]
Last updated Oct 23, 2026 00:00 UTC
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[Trial of device that is not approved or cleared by the U.S. FDA]
Details not publishedSponsor: [Redacted]
Last updated Oct 24, 2026 00:00 UTC
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[Trial of device that is not approved or cleared by the U.S. FDA]
Details not publishedSponsor: [Redacted]
Last updated Oct 24, 2026 00:00 UTC