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137755 trials found · Page 6886 of 6888
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Brentuximab vedotin plus AD in non-bulky limited stage hodgkin lymphoma
CompletedLimited stage Hodgkin lymphoma is a highly curable disease, but standard treatment with ABVD chemotherapy and radiation can lead to late risks of secondary cancers, lung injury, heart injury, and others. This trial eliminates radiation therapy and reduces intensity of chemotherap…
Phase 2 • Sponsor: Massachusetts General Hospital
Last updated Oct 25, 2026 00:00 UTC
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Dose response study of patient controlled analgesia (PCA) of dexmedetomidine in orthopaedic spine surgery patients
CompletedTo study the multimodal protocol combining adjunct dexmedetomidine with oxycodone in intravenous patient-controlled analgesia bolus dosing and effects in patients scheduled for posterolateral lumbar spine fusion with bilateral transpedicular screw instrumentation.
Phase 4 • Sponsor: Turku University Hospital
Last updated Oct 24, 2026 00:00 UTC
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Nitric oxide-mediated cardioprotection during cardiac surgery with cardiopulmonary bypass
CompletedThis prospective randomized study elucidates the effects of exogenous nitric oxide delivered to the extracorporeal circulation circuit for cardioprotection against ischemia-reperfusion injury during coronary artery bypass graft surgery with cardiopulmonary bypass.
Phase 1/2 • Sponsor: Tomsk National Research Medical Center of the Russian Academy of Sciences
Last updated Oct 23, 2026 00:00 UTC
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Deciphering the breast cancer exercise paradox: the role of DNA repair and inflammation
CompletedThis randomized pilot trial studies how well an exercise intervention works in preventing breast cancer from coming back in postmenopausal breast cancer survivors. Regular exercise may be able to train the body to repair deoxyribonucleic acid (DNA) more efficiently and to respond…
Sponsor: City of Hope Medical Center
Last updated Oct 24, 2026 00:00 UTC
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The nucleus hybrid L24 implant system: extended duration post approval study
CompletedThis post approval study evaluates the long term safety and efficacy of the Nucleus Hybrid L24 Implant System in a group of already implanted recipients.
Sponsor: Cochlear
Last updated Oct 23, 2026 00:00 UTC
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Multidimensional characterisation and phenotype discovery in patients with tinnitus based on electronic health records and a tinnitus specialty database
CompletedThis retrospective observational study will use historical electronic health record and tinnitus specialty database data from adult patients with tinnitus seen at the Eye and ENT Hospital of Fudan University between January 2015 and August 2026. The study will identify multidimen…
Sponsor: Eye & ENT Hospital of Fudan University
Last updated Oct 24, 2026 00:00 UTC
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Registre tumeurs endocrine - eurocrine
Recruiting nowThis registry aims to collect informations about patients with endocrine tumors (Thyroid, Parathyroid, Adrenal, Endocrine Pancreas, Endocrine Digestive Tube) who undergo endocrine surgical procedures. This registry is part of the Eurocrine Project.
Sponsor: Central Hospital, Nancy, France
Last updated Oct 24, 2026 00:00 UTC
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Gynaecological emergencies: validation of indicators of activity and quality of care for creation of a network sentinel
CompletedThere is no large-scale data in France or internationally, on the quality of care in gynecological emergencies, or the consequences of delay or misdiagnosis of women's health or on determinants of these delays or misdiagnosis. The creation of a sentinel network for gynecological …
Sponsor: Assistance Publique - Hôpitaux de Paris
Last updated Oct 24, 2026 00:00 UTC
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Brazilian randomized study - impact of preoperative magnetic resonance in the evaluation for breast cancer conservative surgery
CompletedThe aim of this study is to evaluate the ability of MRI to select patients for conservative treatment of breast cancer. Participants: female, over 18 years with breast cancer, stages I, II and III candidates for conservative surgery will be randomly randomized to do MRI or not ac…
Sponsor: University of Sao Paulo General Hospital
Last updated Oct 25, 2026 00:00 UTC
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Role of autoantibodies in spontaneous functional recovery after spinal cord injury
CompletedThe purpose of this study is to determine the autoantibody profiles after spinal cord injury and their role in spontaneous functional recovery.
Sponsor: Hospital Nacional de Parapléjicos de Toledo
Last updated Oct 23, 2026 00:00 UTC
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Magnetic resonance elastography in patients with abdominal aortic aneurysms
Recruiting nowThe main objective of this study is to utilize Magnetic Resonance Elastography (MRE) to determine tissue stiffness of abdominal aortic aneurysms (AAA). For patients with AAA, MRE is a more sensitive and superior method of determining the risk for rupture of AAA based on stiffness…
Sponsor: Ohio State University
Last updated Oct 23, 2026 00:00 UTC
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Timing of glaucoma drainage device implantation with boston keratoprosthesis surgery
Recruiting nowBoston keratoprosthesis (KPro) is a piece of specialized plastic that replace sick cornea (transparent structure at the front of the eye) in patients who have failed or those who are expected to have poor results with traditional corneal transplantation. While the Kpro can offer …
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)
Last updated Oct 25, 2026 00:00 UTC
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Mechanisms and factors responsible for the inhibition of transposons during fetal gonad development in humans
CompletedThis is a single-centre study over 36 months for the inclusion of 30 patients. The selection and inclusion of patients will take place according to the criterion of Medical Termination of Pregnancy at 4 different gestational ages (8-12 weeks of gestation (WG)), 13-16 WG, 17-23 WG…
Sponsor: Centre Hospitalier Universitaire Dijon
Last updated Oct 25, 2026 00:00 UTC
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A MULTIDISCIPLINARY TEAM APPROACH TO IMPROVING LONG TERM OUTCOMES IN SARCOMA SURVIVORS
CompletedPeople who have had a sarcoma removed from the leg often live with weak muscles, stiff joints, and trouble walking. These problems can last for years. Formal medical follow-up usually ends about five years after treatment. Few studies have tested exercise at this stage. This stu…
Sponsor: Curtin University
Last updated Oct 25, 2026 00:00 UTC
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The development and optimization of a cardiac magnetic resonance imaging protocol in a 3 tesla scanner
CompletedIn recent years, evaluating cardiac function with magnetic resonance imaging (MRI) has drawn widespread interest. However, cardiac MRI is prone to severe motion artifacts from cardiac contraction, frequently requiring complex triggering procedures to enhance image quality-a task …
Sponsor: Wang . Jiun-Jie
Last updated Oct 24, 2026 00:00 UTC
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Phase I/II study of the combination of quizartinib (AC220) with 5-Azacytidine or Low-Dose cytarabine for the treatment of patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS)
CompletedThis phase I/II trial studies the side effects and best dose of quizartinib when given in combination with azacitidine or cytarabine in treating patients with acute myeloid leukemia or myelodysplastic syndrome that have come back (relapsed) or are not responding to treatment (ref…
Phase 1/2 • Sponsor: M.D. Anderson Cancer Center
Last updated Oct 25, 2026 00:00 UTC
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A feasibility study of the ability of the neural prosthetic system 2 to provide direct closed loop cortical control of extracorporeal devices through the use of intracortical microstimulation in patients with quadriplegia
OngoingThis research study is being conducted to develop a brain controlled medical device, called a brain-machine interface. The device will provide people with a spinal cord injury some ability to control an external device such as a computer cursor or robotic limb by using their thou…
Sponsor: Richard A. Andersen, PhD
Last updated Oct 25, 2026 00:00 UTC
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Early introduction of solid foods in preterm infants: effects on growth, atopy and neurodevelopment
CompletedIntroduction: Preterm infants with a birth weight less than 1500 grams have special nutritional needs in comparison to full-term neonates. During their stay in the neonatal intensive care unit an increased supply with energy, protein and electrolytes is necessary to establish ade…
Sponsor: Medical University of Vienna
Last updated Oct 23, 2026 00:00 UTC
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Glucose disturbances in the first day of life in preterm infants and health-related quality of life: is there a correlation?
CompletedThe aim of this study is to investigate the correlation between preterm birth, glucose level in the first two hours of life and health related quality of life in the age of 8 months and 7 years
Sponsor: Clinical Hospital Center Rijeka
Last updated Oct 23, 2026 00:00 UTC
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A randomized, double-blind, placebo-controlled, parallel-group clinical study to evaluate the efficacy and safety of ginsenoside Rg3 capsule in prevention of postoperative recurrence of hepatocellular carcinoma
CompletedUsing the subject with hepatocellular carcinoma in the conventional therapy to evaluate the efficacy and safety of ginsenoside Rg3 (20mg BID) and placebo in prevention and treatment of postoperative recurrence of liver cancer,respectively
Sponsor: Shen Feng
Last updated Oct 24, 2026 00:00 UTC