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127005 trials found · Page 6332 of 6351
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Mystery device trial: no data released yet
Knowledge-focused Details not publishedSponsor: [Redacted] • Aim: Knowledge-focused
Last updated Jul 16, 2026 00:00 UTC
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Dimensional changes of autogenous free epithelialized gingival grafts on different bed preparations among dental patients with thin tissue phenotypes: a randomized clinical trial
Not yet recruitingThe goal of this clinical trial is to evaluate the dimensional changes in the short and long-term in patients with thin gum tissues who have gum grafts placed on either denuded bone or gum grafts placed on a bone with some tissues remaining. The main question this study aims to …
Sponsor: University of Iowa
Last updated Sep 09, 2026 16:00 UTC
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Upper extremity vascularized composite allotransplantation: a prospective interventional study evaluating safety, functional outcomes, and Patient-Reported psychosocial outcomes
Not yet recruitingThe primary objective of this study is to evaluate the 5-year (60-month) allograft survival rate of upper extremity vascularized composite allotransplantation performed under the standardized CONSORT clinical protocol.
Sponsor: Yale University
Last updated Sep 09, 2026 16:00 UTC
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Facial vascularized composite allotransplantation: a prospective interventional study evaluating safety, functional outcomes, and Patient-Reported psychosocial outcomes
Not yet recruitingThe primary objective of this study is to evaluate the 5-year (60-month) allograft survival rate of facial vascularized composite allotransplantation performed under the standardized CONSORT clinical protocol.
Sponsor: Yale University
Last updated Sep 09, 2026 16:00 UTC
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Evaluating an innovative tobacco treatment approach for veterans in substance use disorder treatment
Not yet recruitingVeterans with substance use disorders smoke at extraordinarily high rates and have high rates of smoking-related death and disease. It is essential to provide tobacco treatment for Veterans with substance use disorders, but there are unfortunately low rates of smoking treatment e…
Phase 4 • Sponsor: VA Office of Research and Development
Last updated Sep 09, 2026 16:00 UTC
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Evaluation of a wearable sleep monitoring platform with acoustic stimulation for mood regulation
Not yet recruitingThe purpose of this single-site pilot study is to evaluate the feasibility, usability, and technical performance of a wearable sleep-monitoring system that records electroencephalography (EEG) and delivers brief, low-volume sounds during selected stages of sleep. Approximately 3…
Sponsor: University of Houston
Last updated Sep 09, 2026 16:00 UTC
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A multi-center, randomized, double-blind, placebo-controlled, phase 1/2 clinical trial to evaluate the efficacy and safety of EN001 in patients with sarcopenia
Not yet recruitingA Multi-center, Randomized, Double-blind, Placebo-controlled, Phase 1/2 Clinical Trial to Evaluate the Efficacy and Safety of EN001 in Patients with Sarcopenia
Phase 1/2 • Sponsor: ENCell
Last updated Sep 09, 2026 16:00 UTC
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Intergenerational determinants of PCV21 acceptance in adults ≥50 years in panama: knowledge, attitudes, and practices in older adults and their caregivers
Not yet recruitingThis study will look at what adults age 50 years and older in Panama know, think, and do about pneumococcal vaccination, including the 21-valent pneumococcal conjugate vaccine (PCV21). Pneumococcal disease can cause pneumonia and other serious infections, and older adults may be …
Sponsor: Endpoints Site Network
Last updated Sep 09, 2026 16:00 UTC
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Hepatic arterial infusion of autologous tumor infiltrating lymphocytes preconditioned with percutaneous hepatic perfusion with melphalan in patients with melanoma and liver metastases
Not yet recruitingEvaluate the safety and tolerability of treatment with autologous tumor infiltrating lymphocytes (TIL) administered via hepatic arterial infusion and preconditioning with percutaneous hepatic perfusion in patients with liver metastases (but not restricted to) of malignant melanom…
Phase 1 • Sponsor: Vastra Gotaland Region
Last updated Sep 09, 2026 16:00 UTC
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A phase II, plateform study, open-label, evaluating the efficacy and safety of neoadjuvant treatment in patients with surgically resecable pancreatic adenocarcinoma
Not yet recruitingThis is an open master platform trial, which includes multi neo-adjuvant treatment trials, multi-center, national. This platform trial evaluates the major pathological response rate (mPR) after surgery. Intervention: The procedure consists of administering a neoadjuvant treatmen…
Phase 2 • Sponsor: Gustave Roussy, Cancer Campus, Grand Paris
Last updated Sep 09, 2026 16:00 UTC
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Phase 1 First-in-Human Multi-Region clinical trial of ORM-1153 in participants with relapsed or refractory acute myeloid leukemia (AML) or other hematological malignancies with CD123 expression
Not yet recruitingThe goal of this Phase 1 clinical trial is to understand whether a new experimental treatment, called ORM-1153, will be a safe and possibly effective treatment option for participants with blood cancers such as Acute Myeloid Leukemia (AML) which have a particular protein (called …
Phase 1 • Sponsor: Orum Therapeutics USA, Inc.
Last updated Sep 09, 2026 16:00 UTC
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An open-label, single arm, multicenter phase 2 study to evaluate the efficacy and safety of 3D185 monotherapy in subjects with previously treated locally advanced or metastatic cholangiocarcinoma with FGFR2 gene alterations
Not yet recruitingThe purpose of this study is evaluate the efficacy of 3D185 in subjects with advanced/metastatic cholangiocarcinoma with FGFR2 Gene Alterations who have failed at least 1 previous treatment.
Phase 2 • Sponsor: 3D Medicines (Beijing) Co., Ltd.
Last updated Sep 09, 2026 16:00 UTC
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Development and pilot implementation of a novel remote patient monitoring program for cancer patients initiating cancer-directed therapy: the SHIELD (Smart health integration for early life-saving detection)
Not yet recruitingThis clinical trial develops and studies whether using a new remote patient monitoring (RPM) program \[Smart Health Integration for Early Life-saving Detection (SHIELD)\] in cancer practices helps manage infectious complications among cancer patients who are initiating systemic t…
Sponsor: Mayo Clinic
Last updated Sep 09, 2026 16:00 UTC
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Brazilian assessment of technique, utilization, QRS response, and long-term electrical performance of the solia CSP lead
Not yet recruitingThe CSP Registry is a prospective, multicenter, observational, real-world study designed to evaluate the acute feasibility and long-term performance of the Solia CSP lead in Brazilian patients with a clinical indication for permanent ventricular pacing. Approximately 300 adult pa…
Sponsor: Hospital SOS Cardio
Last updated Sep 09, 2026 16:00 UTC
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An "EmbraceMe" self-compassion intervention for body image and mental health of transgender and gender-diverse people in hong kong: a pilot randomized controlled trial
Not yet recruitingThis proposed pilot study aims to evaluate the "EmbraceMe", a self-compassion intervention to improve positive body image and mental health among transgender and gender-diverse (TGD) people in Hong Kong.
Sponsor: Hong Kong Metropolitan University
Last updated Sep 09, 2026 16:00 UTC
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The efficacy of the iWork.COMP among health care professionals: a randomized controlled trial
Not yet recruitingAccording to the literature, the prevalence of anxiety, depression, and/or burnout symptoms among healthcare workers is high. There are several factors than can, directly or indirectly, be related to these symptoms, being the leadership styles one of them. Toxic leadership, as a …
Sponsor: University of Coimbra
Last updated Sep 09, 2026 16:00 UTC
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Opportunistic screening of coronary artery calcium on Non-Gated routine chest CT using artificial intelligence: retrospective external validation and clinical risk stratification
Not yet recruitingThis retrospective, non-interventional study externally validates a pre-trained open-weight deep-learning algorithm (Swin-UNETR) for the opportunistic quantification of coronary artery calcium (CAC) on non-gated routine chest CT scans acquired at a German academic center, and eva…
Sponsor: University of Cologne
Last updated Sep 09, 2026 16:00 UTC
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Hypercapnic burden in adults with obesity undergoing diagnostic polysomnography for suspected obstructive sleep apnea: a prospective observational cohort study
Not yet recruitingObesity-related sleep hypoventilation represents a continuum ranging from isolated nocturnal hypoventilation to obesity hypoventilation syndrome. Current diagnostic criteria rely mainly on dichotomous thresholds and may not adequately reflect cumulative nocturnal carbon dioxide e…
Sponsor: Hospices Civils de Lyon
Last updated Sep 09, 2026 16:00 UTC
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EFFECT OF LACTOBACILLUS ACIDOPHILUS COMBINED WITH INULIN ON COGNITIVE IMPAIRMENT IN PATIENTS WITH OBESITY
Recruiting nowThis randomized crossover clinical trial aims to evaluate the effect of a synbiotic containing Lactobacillus acidophilus and inulin on cognitive function in adults with obesity and mild cognitive impairment. Forty participants aged 30-40 years will be randomly assigned to two gro…
Sponsor: Anahuac University
Last updated Sep 09, 2026 16:00 UTC
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Simulator-Based assessment of driving performance in patients with Parkinson's disease and multiple sclerosis
Not yet recruitingThis prospective observational study investigates whether driving performance measured in a standardized driving simulator differs between people with Parkinson's disease, people with multiple sclerosis, and healthy drivers. Participants will complete a standardized simulated dr…
Sponsor: University Hospital Olomouc
Last updated Sep 09, 2026 16:00 UTC