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Conotruncal heart malformations

Conotruncal heart malformations are a group of congenital cardiac outflow tract anomalies that include such defects as tetralogy of Fallot, pulmonary atresia with ventricular septal defect, double-outlet right ventricle (DORV), double-outlet left ventricle, truncus arteriosus and transposition of the great arteries (TGA), among others. This group of defects is frequently found in patients with 22q11.2 deletion syndrome. A deletion of chromosome 22q11.2 has equally been associated in a subset of patients with various types of isolated non-syndromic conotruncal heart malformations (with the exception of DORV and TGA where this is very uncommon).

1 trial tagged with this condition →

Tetralogy of fallot 34 trials
Persistent truncus arteriosus 8 trials Sub-types →
Double outlet right ventricle 2 trials · 3 incl. sub-types Sub-types →
Pulmonary atresia with ventricular septal defect 1 trial
Abnormal origin of the pulmonary artery 0 trials Sub-types →
Congenital aortopulmonary window 0 trials
Double outlet left ventricle 0 trials
Pulmonary valve agenesis 0 trials Sub-types →