New hope for rare bone cancer: drug combo trial targets toughest cases
NCT ID NCT05830084
First seen Jan 08, 2026 · Last updated May 08, 2026 · Updated 17 times
Summary
This early-phase trial tests whether adding the targeted drug regorafenib to standard chemotherapy is safe and feasible for people with newly diagnosed, widespread Ewing sarcoma. The study enrolls patients aged 2 to 49 with cancer that has spread beyond the lungs, a group with very poor survival rates. The main goal is to find the right dose and check for severe side effects, while also tracking how long patients live without the cancer getting worse.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHU Bordeaux
Bordeaux, France
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Centre Oscar Lambret
Lille, France
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Gustave Roussy
Villejuif, Île-de-France Region, 94805, France
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Institut Curie
Paris, France
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Istituto Nazionale dei Tumori
Milan, 20133, Italy
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Monash Children's Hospital
Clayton, Australia
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Perth Children's Hospital
Perth, WA6009, Australia
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Princess Máxima Center
Utrecht, 113, Netherlands
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Queensland Children's Hospital
Brisbane, Australia
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Rigshospitalet
Copenhagen, DK-2100, Denmark
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Royal Children's Hospital
Parkville, Australia
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Vall d'Hebron University Hospital
Barcelona, 119-12, Spain
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centre Léon Bérard
Lyon, France
Conditions
Explore the condition pages connected to this study.