New hope for rare cancers: targeted drug shrinks tumors in Gene-Matched patients

NCT ID NCT06390852

First seen Sep 30, 2025 · Last updated May 29, 2026 · Updated 31 times

Summary

This study tests a drug called larotrectinib in people with advanced cancers that have a specific genetic change (NTRK fusion). The drug blocks a faulty protein that tells cancer cells to grow. About 35 adults with various cancers, including lymphoma and solid tumors, will receive the drug to see if their tumors shrink or stop growing.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ADVANCED LYMPHOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • ECOG-ACRIN Cancer Research Group

    Philadelphia, Pennsylvania, 19103, United States

Conditions

Explore the condition pages connected to this study.