Université De Sherbrooke

This study tests whether taking a low dose of niacin (vitamin B3) after meals can help reduce fat stored in the liver for people with metabolic fatty liver disease (MASLD). Researchers will compare niacin to a placebo in 36 adults aged 50 to 80. The goal is to see if niacin can r…

This study explores whether repeated cold exposure that causes shivering can improve how the body uses insulin in people with type 2 diabetes. Fifteen adults with type 2 diabetes will undergo 10 days of cold acclimation with shivering. Researchers will measure changes in insulin …

This study looks at whether the time of day you exercise matters for blood sugar control in people with prediabetes. Researchers will compare morning versus late afternoon exercise in 48 adults with prediabetes. They will measure how the body stores fat and uses energy to see if …

This study looks at whether group medical visits can help people with high cholesterol improve their health. About 288 participants will attend shared appointments with a doctor and other patients to learn about lifestyle changes. The goal is to see if this approach lowers choles…

This study tests whether older hospital patients (50+) who get extra visits from a movement specialist walk more, become less frail, and leave the hospital sooner compared to those who get only one visit per day. Researchers will track steps, time spent upright, and frailty level…

This study tests whether the medication dupilumab can help people with moderate asthma achieve complete control, called remission, before their condition becomes severe. Researchers want to see if treating high-risk patients earlier can prevent asthma attacks and lung damage. The…

This study looks at whether two easy, non-invasive tests—a breath test (FeNO) and a blood test—can accurately diagnose asthma in children aged 6 to 17. Currently, diagnosing asthma often requires a hospital-based breathing challenge test that is hard to access. The goal is to see…

This study looks at whether measuring inflammation in the breath and blood can help prioritize who gets asthma tests first. About 1,500 people aged 6 and older with suspected asthma will take a simple breath test and a blood test before their regular lung function tests. The goal…

This study tests a one-time pain management session called Empowered Relief (ER) against usual care for people having elective orthopedic surgery. The goal is to see if ER can lower pain intensity and interference 6 weeks and 3 months after surgery. About 134 adults with chronic …

This study looks at a procedure called thyroid artery embolization (TAE) for people with large goiters that cause symptoms like trouble swallowing or breathing. The goal is to see if blocking the blood supply to the thyroid can shrink the goiter and ease symptoms. The study will …

This study tests whether wearing a knee brace for 72 hours after total knee replacement can reduce pain and help recovery. About 106 adults having knee surgery will either wear the brace or follow standard care. The goal is to see if this simple approach works and if a larger stu…

This study tests whether adding a medium-chain triglyceride (MCT) oil supplement to standard antipsychotic treatment can improve metabolism and symptoms in 15 young adults with first-episode psychosis. The supplement is designed to provide an alternative energy source for the bra…

This study tests whether stimulating the tongue with a gentle device can improve arm function and brain plasticity in people who had a stroke at least 6 months ago. 74 participants will receive either real or sham tongue stimulation combined with a personalized 4-week arm trainin…

This study tests whether a daily movement program led by a kinesiologist can reduce frailty in hospitalized heart patients. Frailty makes people more vulnerable to complications and longer hospital stays. The program includes standing, light exercise, and activity tracking. Resea…

This study tests whether dry needling (inserting fine needles into tight muscles) can reduce pain during intercourse in women with provoked vestibulodynia, a common and often debilitating vulvar pain condition. About 170 women will receive either real or sham dry needling once a …

This study looks at how different weights during resistance exercise affect blood pressure in women aged 50-70 with slightly high blood pressure. Participants will do low-weight and high-weight workouts, and researchers will measure blood pressure changes afterward. The goal is t…

This study follows 330 adults with complex kidney cysts (Bosniak III or IV) to see if simply monitoring them is as safe as surgery. Many of these cysts are not cancer, and surgery carries serious risks. Researchers will compare survival rates over 5 years between those who have s…

This study looks at whether teaching science outside instead of inside a classroom helps children aged 10-12 learn better and feel more connected to nature. About 1000 healthy students will take part in either outdoor or indoor science lessons for 5 weeks. Researchers will measur…

This study is for first-time mothers having a vaginal birth. It aims to see if the length of time the baby's head is crowning (visible at the vaginal opening) is linked to a tear in a key pelvic muscle. Researchers will use ultrasound after birth to check for muscle injury and as…

This study is testing treatments that are already used in intensive care units (ICUs), such as medicines for low blood pressure, platelet transfusions, and nutrition plans. The goal is to find out which approaches work best for critically ill patients. About 5,500 adults in ICUs …

This study looks at how people with lipoprotein lipase deficiency (LPLD) handle fat from food. LPLD causes very high blood fats, leading to belly pain and risk of pancreatitis. Researchers will use special imaging and breath tests to see where dietary fat goes in the body and how…

This study is not testing a treatment or drug. Instead, it trains medical students to conduct phone surveys with 6,000 people in Quebec who had COVID-19. The goal is to gather information on health habits, access to care, and other public health topics to help plan better health …

This study looks at how bariatric surgery changes the way the body stores fat from food, which may explain why type 2 diabetes gets better so quickly after the procedure. Researchers will follow 40 adults who are having bariatric surgery, half with diabetes and half without. They…

This study looks at how a 2-hour bout of sitting affects blood pressure over the next 24 hours in healthy adults aged 18-65. Researchers will measure artery function and blood pressure before, during, and after sitting, and test whether blocking certain artery-relaxing chemicals …