Southeast University, China

This study tests whether changing the breathing machine's settings earlier helps critically ill patients recover faster. About 1,600 adults in ICUs who need a ventilator for at least 2 days will be randomly assigned to either early or standard care. The goal is to see if early ch…

This study tests whether using a special imaging tool (EIT) to set ventilator pressure (PEEP) can reduce deaths in people with severe lung injury (ARDS). About 2,400 adults with moderate-to-severe ARDS will be randomly assigned to EIT-guided PEEP or standard PEEP settings. The ma…

This study tests whether a sedative called remimazolam helps ICU patients on breathing machines recover faster. Researchers will compare it to standard care in 80 adults who need sedation while on a ventilator. The main goal is to see if patients have more days without a breathin…

This study looks at 500 adults with acute respiratory distress syndrome (ARDS), a severe lung condition. Researchers want to see if patients can be grouped into two types based on their body's inflammation levels. The goal is to learn if matching treatments like fluids or steroid…

This study looks at patients with acute brain injury who need a breathing machine. Doctors want to find better ways to predict when these patients can safely breathe on their own. The goal is to improve weaning success and reduce the need for a tracheostomy.

This study observes 1,000 adults in intensive care with moderate-to-severe acute respiratory distress syndrome (ARDS) who are placed on their stomachs (prone positioning) to help them breathe. Researchers aim to learn which patients benefit most, whether it is safe for those with…

This study looks at 40 adults with severe lung injury (ARDS) who need a breathing machine and are placed face-down to help their lungs. Researchers want to see if feeding through a tube into the stomach or deeper into the small intestine helps them get enough nutrition. They will…

This study looks at how the time it takes for a patient's lungs to empty during breathing machine support affects oxygen and blood flow in the lungs. Researchers will study 60 adults with acute respiratory distress syndrome (ARDS) who have been on a ventilator for less than 72 ho…