Children's Mercy Hospital Kansas City

This study is testing a new portable MRI machine that uses a very low magnetic field. It is designed to be safer and less scary for children, as it does not require a special room or removal of metal items. Researchers will compare images from this low-field MRI to those from sta…

This study looks at whether the measles, mumps, and rubella (MMR) vaccine is safe and works well in children aged 1 to 17 who have had a heart transplant. About 60 participants will receive the standard MMR vaccine. Researchers will check for side effects and measure immune respo…

This study tests a wearable device called ViBandz that delivers gentle vibrations to help children with neurological conditions improve movement in their arms or legs. About 30 children aged 6 months to 17 years will use the device at home after a therapy session. Researchers wil…

This study adapts a group program called Regulating Together for children aged 8–12 with autism and intellectual disability who struggle with emotion dysregulation. The goal is to teach practical strategies to reduce irritability, aggression, and other challenging behaviors. Ten …

This study looks at two ways of taking progesterone to see which leads to better menstrual bleeding patterns in adolescents with Turner Syndrome who also have primary ovarian insufficiency. About 40 participants will be followed to track bleeding and any related distress. The goa…

This study tests whether live, group exercise classes delivered via video chat can help teens with congenital heart disease get fitter and healthier. 74 teens aged 12-19 will either join 12 weeks of remote exercise sessions or receive standard advice. The goal is to see if the re…

This study tests whether a home-based virtual reality (VR) program that uses brain activity to guide relaxing imagery is practical and helpful for teens aged 10-16 with migraines. Participants will use a VR headset three times a week for four weeks. Researchers will see if teens …

This study tests a group program to help teens with Prader-Willi Syndrome (PWS) and their families handle emotional challenges like irritability, meltdowns, and anxiety. Ten teens aged 13-17.5 with a confirmed PWS diagnosis will attend weekly 90-minute sessions. The goal is to se…

This study tests a short therapy called FACT (Focused Acceptance and Commitment Therapy) to see if it can improve mental health for parents of children with pediatric feeding disorder. About 80 parents will be randomly assigned to FACT or a placebo program. The goal is to reduce …

This study tests a new pillow-like device that helps babies with tracheostomies (breathing tubes) lie on their stomachs for tummy time. Researchers want to see if the device fits well, is comfortable, and allows the baby to breathe safely. Parents and healthcare providers will sh…

This study is testing a new, low-field MRI scanner on 500 children to see if it can produce clear brain images without the need for sedation. The goal is to compare this portable scanner to standard MRI, CT, or ultrasound. If successful, it could make brain imaging safer and more…

This study looks at how a drug called naltrexone changes brain activity in teens aged 13-21 with eating disorders like bulimia or binge eating. Participants will have brain scans after taking the drug or a placebo to see if the scans can measure the drug's effect. The goal is to …

This study tests a new survey tool called Spotlight AQ for teens and young adults (ages 16-25) with type 1 diabetes. Participants use the survey before two regular clinic visits to see if it helps lower their blood sugar levels (A1c) and if patients and doctors like using it. The…

This study examines how fat in the liver changes the way children process the cholesterol drug rosuvastatin. Researchers will measure liver fat using MRI and track drug levels and response in 50 children aged 8-21 with high cholesterol. The goal is to understand if liver fat incr…

This study looks at how liver congestion and scarring affect the way the body processes medications in children, teens, and young adults who have had Fontan surgery for a single ventricle heart condition. Researchers will measure how two common drugs, sildenafil and pravastatin, …